Results 301 to 310 of about 135,756 (330)
Some of the next articles are maybe not open access.

Related searches:

Myeloid neoplasms with germ line RUNX1 mutation

International Journal of Hematology, 2017
Familial platelet disorder with propensity to myeloid malignancies (FPD/AML) is an autosomal dominant disorder characterized by quantitative and/or qualitative platelet defects with a tendency to develop a variety of hematological malignancies. Heterozygous germ line mutations in the RUNX1 gene are responsible genetic events for FPD/AML. Notably, about
Yoshihiro, Hayashi   +3 more
openaire   +2 more sources

Familial Gastrointestinal Stromal Tumors and Germ-Line Mutations

New England Journal of Medicine, 2007
To the Editor: Gastrointestinal stromal tumors may be sporadic or inherited in an autosomal dominant manner, alone or as a component of a syndrome associated with other tumors, such as in the conte...
MCWHINNEY SR   +2 more
openaire   +3 more sources

Germ-Line Mutations, Pancreatic Inflammation, and Pancreatic Cancer

Clinical Gastroenterology and Hepatology, 2009
The fundamental problem underlying pancreatic cancer is altered genetics. Rare germ-line mutations lead to familial cancer syndromes that may include pancreatic cancer. But why do some people develop pancreatic cancer while others develop cancer in other organs, or not at all?
David, Whitcomb, Julia, Greer
openaire   +2 more sources

Germ line mutations associated with breast cancer susceptibility

European Journal of Cancer, 2001
Laboratory-based research in germ line mutations associated with breast cancer susceptibility is rapidly being integrated into clinical practice with profound implications. A Medline search was performed for all relevant articles published since 1990. Where appropriate, historical articles referenced in those identified were also reviewed.
P T, Iau, R D, Macmillan, R W, Blamey
openaire   +2 more sources

Germ-line and somatic PTPN11 mutations in human disease

European Journal of Medical Genetics, 2005
Reversible protein tyrosyl phosphorylation of cell surface receptors and downstream intracellular transducers is a major regulatory mechanism used to modulate cellular responses to extracellular stimuli, and its deregulation frequently drives aberrant cell proliferation, survival and/or differentiation.
Marco, Tartaglia, Bruce D, Gelb
openaire   +2 more sources

Home - About - Disclaimer - Privacy