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Surgical Clinics of North America, 2006
The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
Nuria, Pardo García +2 more
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The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
Nuria, Pardo García +2 more
+6 more sources
Seminars in Neurology, 2023
AbstractIntracranial germ cell tumors are rare tumors occurring in adolescents and young adults, which include germinomas and non-germinomatous type germ cell tumors (NGGCT). In the past few decades, cooperative trial groups in Europe and North America have developed successful strategies to improve survival outcomes and decrease treatment-related ...
Teri Danielle You Ying, Yeoh +4 more
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AbstractIntracranial germ cell tumors are rare tumors occurring in adolescents and young adults, which include germinomas and non-germinomatous type germ cell tumors (NGGCT). In the past few decades, cooperative trial groups in Europe and North America have developed successful strategies to improve survival outcomes and decrease treatment-related ...
Teri Danielle You Ying, Yeoh +4 more
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New England Journal of Medicine, 2007
Testicular cancer is rare, accounting for 1% to 2% of all male malignancies. Nearly 90% to 95% of tumors arising in testis are germ cell in origin. Other sites of malignant germ cell tumors include the retroperitoneum, mediastinum, sacrococcygeal region, and pineal gland. The highest incidence is seen in Scandinavian countries, particularly Denmark (1).
De Giorgi U, Pedrazzoli P, Rosti G
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Testicular cancer is rare, accounting for 1% to 2% of all male malignancies. Nearly 90% to 95% of tumors arising in testis are germ cell in origin. Other sites of malignant germ cell tumors include the retroperitoneum, mediastinum, sacrococcygeal region, and pineal gland. The highest incidence is seen in Scandinavian countries, particularly Denmark (1).
De Giorgi U, Pedrazzoli P, Rosti G
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Hematology/Oncology Clinics of North America, 1992
The development of modern surgical staging and effective chemotherapy regimens has markedly improved outcome of treatment of ovarian germ cell tumors. Almost all patients with completely resected tumors will survive their disease. Those with tumors other than dysgerminoma should all receive adjuvant chemotherapy. Patients with stage IA dysgerminoma can
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The development of modern surgical staging and effective chemotherapy regimens has markedly improved outcome of treatment of ovarian germ cell tumors. Almost all patients with completely resected tumors will survive their disease. Those with tumors other than dysgerminoma should all receive adjuvant chemotherapy. Patients with stage IA dysgerminoma can
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Current Opinion in Oncology, 2005
This review provides an overview of some of the recent pre-clinical and clinical developments in germ cell tumors.Recent epidemiological studies highlight the variations in the geographic and ethnic distribution of germ cell tumors and the changing incidence of seminoma versus nonseminoma in the population. Additional studies are continuing to identify
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This review provides an overview of some of the recent pre-clinical and clinical developments in germ cell tumors.Recent epidemiological studies highlight the variations in the geographic and ethnic distribution of germ cell tumors and the changing incidence of seminoma versus nonseminoma in the population. Additional studies are continuing to identify
openaire +3 more sources
Current Pediatric Reviews, 2015
Excluding hemangiomas, germ cell tumors (GCTs) are the most common neoplasm in neonates, comprising a wide range of benign and malignant tumors with unique histological diversity. Although these tumors are relatively rare, antenatal ultrasonography has increased their detection before birth.
John A, Sandoval, Regan F, Williams
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Excluding hemangiomas, germ cell tumors (GCTs) are the most common neoplasm in neonates, comprising a wide range of benign and malignant tumors with unique histological diversity. Although these tumors are relatively rare, antenatal ultrasonography has increased their detection before birth.
John A, Sandoval, Regan F, Williams
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Current Problems in Cancer, 1999
Malignant germ cell tumors are relatively uncommon, accounting for approximately 3% of all childhood malignancies. Occurring with an incidence of approximately 4 per million among children less than 15 years of age, they account for approximately 225 new cases per year in the United States. Germ cell tumors occur in both gonadal and extragonadal sites,
F J, Rescorla, P P, Breitfeld
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Malignant germ cell tumors are relatively uncommon, accounting for approximately 3% of all childhood malignancies. Occurring with an incidence of approximately 4 per million among children less than 15 years of age, they account for approximately 225 new cases per year in the United States. Germ cell tumors occur in both gonadal and extragonadal sites,
F J, Rescorla, P P, Breitfeld
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1997
Germ cell tumors historically have been considered to be a single nosologic category comprising tumors with different histologic manifestations and different degrees of malignancy and arising at different sites of origin. Only in the last decade has the biologic heterogeneity of germ cell tumors been recognized and addressed.
E J, Perlman, C, Kretschmar
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Germ cell tumors historically have been considered to be a single nosologic category comprising tumors with different histologic manifestations and different degrees of malignancy and arising at different sites of origin. Only in the last decade has the biologic heterogeneity of germ cell tumors been recognized and addressed.
E J, Perlman, C, Kretschmar
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