Results 161 to 170 of about 220,960 (266)

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, EarlyView.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources

Genetic Characterization of Primordial Germ Cells in Spotted Sea Bass (<i>Lateolabrax maculatus</i>). [PDF]

Genes (Basel)
Guo J, Yan L, Zhao C, Zhang B, Zhang B, Qiu L.   +5 more
europepmc   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

Animal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen, Xijia Shao, Xiulin Zhang, Ningning Zhang, Xiao Chen, Guangxin Yue, Jiangping Song   +6 more
wiley   +1 more source

Histological analysis of cheetah testes focused on the germ cells and Sertoli cells. [PDF]

J Vet Med Sci
Shimizu R, Ota K, Toda K, Yoshimoto Y, Sato S, Shimada K, Tanaka R, Hamabe L, Nagaoka K, Yamamoto Y.   +9 more
europepmc   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Selinexor, a selective inhibitor of nuclear export, shows anti-proliferative and anti-migratory effects on male germ cells in vitro. [PDF]

BMC Pharmacol Toxicol
Öztatlıcı M, Zada PR, Çolaksel RB, Halıcıoğlu BŞ, Öztatlıcı H.   +4 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Establishment of an efficient electroporation-based knock-in system in chicken primordial germ cells and a rapid method for positive cell selection. [PDF]

Poult Sci
Lv X, Wei Q, Sun J, Tan X, Gong W, Yao Z, Niu Y, Song J, Li B, Zuo Q.   +9 more
europepmc   +1 more source

Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development. [PDF]

Mol Reprod Dev
Bhattacharya I, Nalinan LK, Anusree KV, Saleel A, Khamamkar A, Dey S.   +5 more
europepmc   +1 more source

Acute testicular hyperthermia leads to rapid loss of global piRNA and a concurrent increase in LINE1 activity within heat sensitive male germ cells. [PDF]

Mob DNA
Robinson BR, Netherton JK, Ogle RA, Burnard SM, Williams GE, Tennant GM, Hussein M, Lee HJ, Velkov T, Baker MA.   +9 more
europepmc   +1 more source