Results 251 to 260 of about 414,793 (308)
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New England Journal of Medicine, 2007
Testicular cancer is rare, accounting for 1% to 2% of all male malignancies. Nearly 90% to 95% of tumors arising in testis are germ cell in origin. Other sites of malignant germ cell tumors include the retroperitoneum, mediastinum, sacrococcygeal region, and pineal gland. The highest incidence is seen in Scandinavian countries, particularly Denmark (1).
De Giorgi U, Pedrazzoli P, Rosti G
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Testicular cancer is rare, accounting for 1% to 2% of all male malignancies. Nearly 90% to 95% of tumors arising in testis are germ cell in origin. Other sites of malignant germ cell tumors include the retroperitoneum, mediastinum, sacrococcygeal region, and pineal gland. The highest incidence is seen in Scandinavian countries, particularly Denmark (1).
De Giorgi U, Pedrazzoli P, Rosti G
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Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1995
Whether germ cells succeed in making eggs or sperm depends both on their genetic constitution and on the tissue environment in which they develop. The decision as to whether it is oogenesis or spermatogenesis on which they initially embark depends only on their environment, however, and not at all on their own chromosomes.
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Whether germ cells succeed in making eggs or sperm depends both on their genetic constitution and on the tissue environment in which they develop. The decision as to whether it is oogenesis or spermatogenesis on which they initially embark depends only on their environment, however, and not at all on their own chromosomes.
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Annals of Internal Medicine, 1981
Excerpt To the editor: The letters by Page (1) and Newcomer (2) in the May issue and the comments by other physicians in response to our article on unrecognized germ cell cancers (3) warrant a repl...
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Excerpt To the editor: The letters by Page (1) and Newcomer (2) in the May issue and the comments by other physicians in response to our article on unrecognized germ cell cancers (3) warrant a repl...
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2019
Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
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Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
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Seminars in Reproductive Medicine, 2005
Transplantation of male germ line stem cells from a fertile donor to the testis of an infertile recipient restores donor-derived spermatogenesis in the recipient testis. The resulting sperm pass the donor genotype to the offspring of the recipient. Germ cell transplantation helped to elucidate the biology of male germ line stem cells and their niche in
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Transplantation of male germ line stem cells from a fertile donor to the testis of an infertile recipient restores donor-derived spermatogenesis in the recipient testis. The resulting sperm pass the donor genotype to the offspring of the recipient. Germ cell transplantation helped to elucidate the biology of male germ line stem cells and their niche in
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Seminars in Diagnostic Pathology, 2005
Germ Cell Tumors (GCT) represent an important group of mediastinal tumors. Because of genetic characteristics and behavior have been divided in prepubertal and postpubertal tumors, and their origin remains controversial. The genetic changes are diverse, but the most frequent is i (12p), and can be associated to gonadal disgenesis.
Hugo, Domínguez Malagón +1 more
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Germ Cell Tumors (GCT) represent an important group of mediastinal tumors. Because of genetic characteristics and behavior have been divided in prepubertal and postpubertal tumors, and their origin remains controversial. The genetic changes are diverse, but the most frequent is i (12p), and can be associated to gonadal disgenesis.
Hugo, Domínguez Malagón +1 more
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Surgical Clinics of North America, 2006
The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
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The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
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2006
Primordial germ cells, which carry the responsibility for perpetuation of the species, are set aside from their somatic neighbors very early in mammalian embryonic development. The founder population of germ cells is rare and difficult to identify and isolate in quantities suitable for molecular and biochemical analysis, thereby highlighting the ...
Niels, Geijsen, George Q, Daley
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Primordial germ cells, which carry the responsibility for perpetuation of the species, are set aside from their somatic neighbors very early in mammalian embryonic development. The founder population of germ cells is rare and difficult to identify and isolate in quantities suitable for molecular and biochemical analysis, thereby highlighting the ...
Niels, Geijsen, George Q, Daley
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Immature germ cell conception—in vitro germ cell manipulation
Best Practice & Research Clinical Endocrinology & Metabolism, 2000Experimental studies in laboratory animals have shown that successful conception can be achieved by fertilizing oocytes with immature male germ cells. This gave rise to the concept that immature germ cells recovered from the testes of azoospermic men with maturation arrest may be used for assisted reproduction.
J, Tesarik, C, Mendoza, E, Greco
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Current Opinion in Oncology, 1999
The publication of the proceedings of Fourth Workshop on Carcinoma in situ was an impressive leap in our understanding of the interaction between prenatal and postpubertal factors in the development of germ cell cancer as well as increased insight into the molecular events that are involved in the development of these tumors. From this work, physicians
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The publication of the proceedings of Fourth Workshop on Carcinoma in situ was an impressive leap in our understanding of the interaction between prenatal and postpubertal factors in the development of germ cell cancer as well as increased insight into the molecular events that are involved in the development of these tumors. From this work, physicians
openaire +2 more sources