Results 81 to 90 of about 3,781,098 (345)
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Musicology and German National Identity
Central Europe, 2019 This article explores the concept of German national identity as it has been used by musicologists and offers an alternative, fuller understanding of that concept by placing it in its late eighteenth-century context.
Emily Jane Clink
doaj
Constraints on anomalous color dipole operators from Higgs boson production at the LHC
, 2013 Physics beyond the standard model (SM) can be parameterized with an effective Lagrangian that respects the symmetries of the standard model and contains many operators of dimension six.
Hayreter, Alper, Valencia, German
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
T-odd correlations from top-quark CEDM in lepton plus jets top-pair events
, 2016 There exist several recent studies of the top-quark CEDM in the context of searching for CP violating signals in top-quark pair production at the LHC. Most of these studies constrain the CEDM either from deviations in the top-pair cross section from its ...
Hayreter, Alper, Valencia, German
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Intergenerational service-learning through virtual exchange across a foreign language program
Journal of Virtual ExchangeThis paper reports on the implementation of intergenerational service-learning (SL) through virtual exchange (VE) across a German as a foreign language program at a private research institution on the East Coast in the U.S.
Carolin Fuchs
doaj +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
İlkokul Çağında Çoklu Dil Eğitimine Yönelik Veli Görüşlerinin İncelenmesi
Van Yüzüncü Yıl Üniversitesi Eğitim Fakültesi DergisiGünümüzün küreselleşen dünyasında kültürel çeşitliliği deneyimlemek ve gelecek planları kolay bir şekilde gerçekleştirebilmek için birden fazla yabancı dil öğrenmenin önemi büyüktür.
Tugba Aydın Yıldız +1 more
doaj +1 more source
Ritorno radiativo per la misura di R: come e perche
, 2003 The measurement of the pion form factor and, more generally, of the cross section for electron--positron annihilation into hadrons through the radiative return has become an important task for high luminosity colliders such as the $\Phi$- or $B$-meson ...
Rodrigo, German
core