Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
The use of urodynamic studies to help sort out bladder problems [PDF]
, 1997 Urodynamic studies are performed as part of the clinical investigation of selected patients with lower urinary tract dysfunction. These studies provide the clinician with information about lower urinary tract function and allow a more scientific approach
German, Karl Andrew
core
Constraints on anomalous color dipole operators from Higgs boson production at the LHC
, 2013 Physics beyond the standard model (SM) can be parameterized with an effective Lagrangian that respects the symmetries of the standard model and contains many operators of dimension six.
Hayreter, Alper, Valencia, German
core +1 more source
Detection and Characterization of Alongshan Virus in Ticks and Tick Saliva from Lower Saxony, Germany with Serological Evidence for Viral Transmission to Game and Domestic Animals [PDF]
, 2023 Cara Leonie Ebert +23 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Validity of two Higgs doublet models with a scalar color octet up to a high energy scale
, 2017 We have recently studied theoretical constraints on the parameters of a 2HDM augmented with a color-octet scalar. In this paper we consider the consequences of requiring the model to remain valid up to very high energy scales, such as the GUT scale.
Cheng, Li, Valencia, German
core +1 more source
Minor stroke in large vessel occlusion: A matched analysis of patients from the German Stroke Registry–Endovascular Treatment (GSR‐ET) and patients from the Safe Implementation of Treatments in Stroke–International Stroke Thrombolysis Register (SITS‐ISTR) [PDF]
, 2022 Katharina Feil +15 more
openalex +1 more source