Results 51 to 60 of about 177,757 (312)

Using Natural Sciences for Cultural Expansion: The National Socialist Agenda for the Balkans

open access: yesHistorical Review, 2008
This article highlights the political merit natural sciences were awarded under the totalitarian regime of Nazi Germany and their propagandistic role in Hitler's foreign policy agenda for the Balkans, a region which was expected to replace Germany's ...
Maria Zarifi
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Image of Christopher Columbus and the Discovery of America in the German Opera in the Third Reich

open access: yesMemoria y Civilización, 2017
On July 13, 1933, Bavarian Radio broadcast the opera Columbus of the German composer Werner Egk. This opera was the first of three approaches to the Hispanic world of this composer, whose rise in the musical world of his country coincided with the ...
José Elías Gutiérrez Meza
doaj   +1 more source

Learning through the waste: olfactory cues from the colony refuse influence plant preferences in foraging leaf-cutting ants [PDF]

open access: yes, 2016
Leaf-cutting ants learn to avoid plants initially harvested if they proved to be harmful for their symbiotic fungus once incorporated into the nest.
Arenas, Andres, Roces, Flavio
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Interculturalità e Humanitätsgedanke: dalla prospettiva tardo-illuminista di Herder agli sguardi sull’Africa nel romanzo postcoloniale tedesco “Usambara” di Christof Hamann (2007)

open access: yesAltre Modernità, 2019
As this contribution shows, the increasing production of German-language postcolonial novels over the last fifteen years has contributed to enhance the dialogue with the vast debate on cultural anthropology promoted by the European late Enlightenment ...
Elena Agazzi
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

German Colonialism Revisited

open access: yes, 2014
German Colonialism Revisited brings together military historians, art historians, literary scholars, cultural theorists, and linguists to address a range of issues surrounding colonised African, Asian, and Oceanic people's creative reactions to and interactions with German colonialism.
openaire   +1 more source

The 'Cat's Paw of Dictatorship': State Security and Self-Rule in the Gold Coast, 1948 to 1957 [PDF]

open access: yes, 2019
On February 28th, 1948, a deadly police shooting at a veteran’s demonstration in the Gold Coast sparked three days of rioting in the capital city of Accra and surrounding communities. It was the first crisis of its kind for the British colony and a clear
Arnold, Chase
core  

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