Results 41 to 50 of about 1,134,243 (305)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Methodological Aspects of Teaching German as a Pluricentric Language

Vestnik za Tuje Jezike, 2023
This scientific article explores the methodological aspects of teaching German as a pluricentric language, with a specific focus on the role of the Austrian national variant.
Mykola Karpik, Oksana Pavlychko
doaj   +1 more source

Language Report German

, 2023
AbstractGerman is the second most widely spoken language in the EU. The last decade has seen strongly perceptible language change, trending towards the simplification of the grammatical system, a rapidly growing number of anglicisms, a decreasing prevalence of dialects, and an increase in socio-political debates on matters such as language policies and
Hegele, Stefanie, Heinisch, Barbara, Popp, Antonia, Marheinecke, Katrin, Rios, Annette, Gromann, Dagmar, Volk, Martin, Rehm, Georg   +7 more
openaire   +2 more sources

Non-native children speech recognition through transfer learning

, 2018
This work deals with non-native children's speech and investigates both multi-task and transfer learning approaches to adapt a multi-language Deep Neural Network (DNN) to speakers, specifically children, learning a foreign language.
Falavigna, Daniele, Giuliani, Diego, Gretter, Roberto, Matassoni, Marco   +3 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Informed consent at stake? Language barriers in medical interactions with immigrant anaesthetists: a conversation analytical study

BMC Health Services Research, 2019
Background Language barriers in doctor-patient interactions are still an understudied phenomenon. This is particularly true concerning interactions with immigrant physicians who are learners of the patient’s language; there is a lack of research even ...
Damaris Borowski, Uwe Koreik, Udo Ohm, Claudia Riemer, Niels Rahe-Meyer   +4 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Exploring the relationship between flow experience and passive learning resistance in learning German

Humanities & Social Sciences Communications
This study examines the correlation between students’ flow experience and passive resistance to learning in the context of German as a foreign language education. A quantitative, descriptive-correlational research design was employed. Data were collected
Ferdiye Çobanoğulları, Merve Çıldır   +1 more
doaj   +1 more source

What linguists always wanted to know about german and did not know how to estimate [PDF]

, 2006
This paper profiles significant differences in syntactic distribution and differences in word class frequencies for two treebanks of spoken and written German: the TüBa-D/S, a treebank of transliterated spontaneous dialogues, and the TüBa-D/Z treebank of
Hinrichs, Erhard, Kübler, Sandra
core  

Production of L3 Vowels: Is it Possible to Separate them from L1 and L2 Sounds? [PDF]

, 2015
It is incontrovertible that acquisition of a sound system of a second language is always a complex phenomenon and presents a great challenge for L2 learners (e.g. Rojczyk, 2010a). There are numerous studies (e.g.
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core   +2 more sources