Results 41 to 50 of about 1,157,033 (353)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The Multimodal Constitution of Objects: How Church Viewing is Accomplished

Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2017
Based on a single case analysis, this essay examines the question of what the structure of a church viewing is like. Within a theoretical framework which conceptualizes the church viewing as a cultural practice, "object constitution" is regarded as a ...
Reinhold Schmitt
doaj   +1 more source

Cross-Linguistic Influences of Learning German in Finnish and German Upper Secondary Schools

Journal of Linguistics and Language Teaching, 2023
The aim of this study is to find out what importance upper secondary school learners of German attach to the cross-linguistic influence (CLI) regarding specific aspects of German language learning in Finland and Germany.
Esa M. Penttinen, Heiner Böttger
doaj   +1 more source

The canonization of German-language digital literature [PDF]

, 2009
In his paper, "The Canonization of German-language Digital Literature," Florian Hartling discusses "Net Literature," a relatively young phenomenon, that has its roots in experimental visual and concrete poetry and hypertext.
Hartling, Florian
core  

Überidentifikation von Lernstörungen bei Kindern mit Deutsch als Zweitsprache. Implikationen für die Normierung von standardisierten Schulleistungstests [PDF]

, 2016
This German prevalence study examined disproportionate representation of language- minority students among children identified with learning disorder (LD) according to ICD-10 (WHO, 1992). Most German school achievement tests used in LD diagnostics do not
Brandenburg, Janin, Fischbach, Anne, Hasselhorn, Marcus, Labuhn, Andju Sara, Rietz, Chantal Sabrina, Schmid, Johanna   +5 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Exploring the relationship between flow experience and passive learning resistance in learning German

Humanities & Social Sciences Communications
This study examines the correlation between students’ flow experience and passive resistance to learning in the context of German as a foreign language education. A quantitative, descriptive-correlational research design was employed. Data were collected
Ferdiye Çobanoğulları, Merve Çıldır   +1 more
doaj   +1 more source

Informed consent at stake? Language barriers in medical interactions with immigrant anaesthetists: a conversation analytical study

BMC Health Services Research, 2019
Background Language barriers in doctor-patient interactions are still an understudied phenomenon. This is particularly true concerning interactions with immigrant physicians who are learners of the patient’s language; there is a lack of research even ...
Damaris Borowski, Uwe Koreik, Udo Ohm, Claudia Riemer, Niels Rahe-Meyer   +4 more
doaj   +1 more source