Results 31 to 40 of about 133,668 (277)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Quo vadis AGMB? Ergebnisse der Online-Mitgliederbefragung 2019 sowie Ausblick auf mögliche Konsequenzen für die AGMB

open access: yesGMS Medizin – Bibliothek – Information, 2019
Traditionally, the yearly conference of the Arbeitsgemeinschaft für Medizinisches Bibliothekswesen e.V. (German Medical Library Association) is the central continuing education event for librarians and information specialists working in all types of ...
Reimann, Iris, Semmler-Schmetz, Martina
doaj   +1 more source

Autorenregister: AGMB aktuell 1997-2000, medizin - bibliothek - information 2001 [PDF]

open access: yes, 2002
Index of authors of the publications of the German Medical Libraries Association (1997-2001): http://www.agmb.de/mbi/indexneu.html, http://www.agmb.de/mbi/mbiauswahl ...
Bauer, Bruno
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

10 Fragen von Bruno Bauer an Dietrich Nelle, den Interimsdirektor von ZB MED – Informationszentrum Lebenswissenschaften

open access: yesGMS Medizin – Bibliothek – Information, 2018
ZB MED – Information Center for Life Sciences is the largest library worldwide in the field of life sciences. From October 2016 to June 2018 Dietrich Nelle was its interim managing director.
Bauer, Bruno, Nelle, Dietrich
doaj   +1 more source

Special Libraries, November 1952 [PDF]

open access: yes, 1952
Volume 43, Issue 9https://scholarworks.sjsu.edu/sla_sl_1952/1008/thumbnail ...
Special Libraries Association
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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