Results 31 to 40 of about 16,417,253 (231)

Hospital libraries, pharmaceutical libraries, veterinary medical libraries

open access: yes, 2011
The recent issue 1-2/2011 of GMS Medizin - Bibliothek - Information has a focus on hospital libraries, pharmaceutical libraries and veterinary medical libraries.
Bauer, B
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

10 Fragen von Bruno Bauer an Dietrich Nelle, den Interimsdirektor von ZB MED – Informationszentrum Lebenswissenschaften

open access: yesGMS Medizin – Bibliothek – Information, 2018
ZB MED – Information Center for Life Sciences is the largest library worldwide in the field of life sciences. From October 2016 to June 2018 Dietrich Nelle was its interim managing director.
Bauer, Bruno, Nelle, Dietrich
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Cooperation of medical libraries

open access: yes, 2018
The focus of the current issue 1-2/2018 of GMS Medizin - Bibliothek - Information is on cooperation of medical libraries. The authors in this issue are Martina Semmler-Schmetz, Jutta Matrisciano, Oliver Weiner & Iris Reimann (Cooperations with internal ...
Bauer, B
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

THE DEVELOPMENT OF UKRAINIAN MEDICAL SCIENTIFIC ORGANIZATION THROUGH THE CENTURIES (ON THE 120th ANNIVERSARY OF ITS FOUNDING)

open access: yesProceedings of the Shevchenko Scientific Society: Medical Sciences, 2018
Introduction. February 7th, 2018 marks 120 years since the foundation of the first Ukrainian medical scientific society “The Medical Commission of the Shevchenko Scientific Society.” Its original periodical journal  “Medical Collection” was initiated ...
Oksana Zayachkivska, Vassyl Lonchyna
doaj   +1 more source

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