Results 41 to 50 of about 1,287 (170)

Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems

open access: yesAdvanced Materials, EarlyView.
DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther   +9 more
wiley   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

open access: yesAdvanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti   +13 more
wiley   +1 more source

Twisted MoS2 Bilayers as Functional Elements in Memtransistors: Hysteresis, Optical Signatures, and Photocurrent Kinetics

open access: yesAdvanced Electronic Materials, EarlyView.
ABSTRACT Layered 2D materials are considered as promising for memristive applications due to their ultimate vertical scalability compared to conventional semiconductor films and pronounced hysteresis properties. Bias‐resolved Raman and Photoluminescence mapping is used to quantify strain from phonon shifts and carrier density from the exciton‐trion ...
Vladislav Kurtash   +4 more
wiley   +1 more source

Gatekeepers of the Future: The Role of Corporate Venture Capital in Corporate Artificial Intelligence Adoptions

open access: yesStrategic Change, EarlyView.
ABSTRACT This study extends absorptive capacity research by showing how corporate venture capital (CVC) investments enable corporate artificial intelligence (AI) adoption through collaboration pathways, delineated in four adoption archetypes that explain how heterogeneous AI knowledge is absorbed.
Louisa A. Müller   +2 more
wiley   +1 more source

Clinical Progression in Alpha‐Synuclein Positive LRRK2‐PD and Sporadic Parkinson's Disease: A Longitudinal Analysis

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background LRRK2‐Parkinson's disease (LRRK2‐PD) is biologically heterogeneous with approximately 30% lacking aggregated alpha synuclein (αSyn) in cerebrospinal fluid by seed amplification assay (SAA). Prior work has suggested slower progression in LRRK2‐PD compared to sporadic PD (sPD).
Lucy A. Morse   +224 more
wiley   +1 more source

Aus der AGMB

open access: yesGMS Medizin – Bibliothek – Information, 2019
We look back to a successful Annual Meeting of the German MLA (AGMB) 2019 in Göttingen. A new executive board was elected as well as the management of the working groups for the period 2019 to 2021.
Reimann, Iris
doaj   +3 more sources

German MLA (AGMB) competition "Pioneer projects in medical libraries" 2022 - announcement

open access: yes, 2021
The competition "Pioneer projects in medical libraries" 2022 is announced.Der Wettbewerb "Leuchtturmprojekte an Medizinbibliotheken" wird für 2022 erneut ...
Wöckel, C
core   +1 more source

Toward Free‐Breathing Renal CEST MRI: Preclinical Evaluation of a Novel Prospective Respiratory Triggering Approach

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Endogenous renal chemical exchange saturation transfer (CEST) imaging enables contrast‐agent‐free assessment of renal metabolism but is highly sensitive to respiratory motion. Existing approaches, such as timed breathing, require high patient compliance or preclinical mechanical ventilation, limiting clinical translation.
Patrik Jan Gallinnis   +12 more
wiley   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

open access: yesObesity, EarlyView.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín   +4 more
wiley   +1 more source

Effect of oxygen and nanoparticles on human skin and colon cells exposed to synchrotron‐based X‐ray FLASH beams

open access: yesJournal of Synchrotron Radiation, EarlyView.
Most cancer patients will be treated by radiotherapy, and recent findings suggest that delivering radiation at `FLASH' ultra‐high dose rates reduces damage to healthy tissues while still damaging the tumour. This project experimentally validates the reduced healthy tissue damage of FLASH radiotherapy on cells using synchrotron‐based beams, which will ...
Moshi Geso   +9 more
wiley   +1 more source

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