Results 211 to 220 of about 338,748 (310)

Quality of Life and Return to Work After Radiotherapy in Young Adults With Head-and-Neck Cancer-A Bicentric Cross-Sectional Observational Study. [PDF]

Cancer Med
Pannenbecker C, Seidel C, Zou J, Schnell D, Wichmann G, Becker C, Klagges S, Schäfer H, Knopf A, Dietz A, Grosu AL, Mehnert-Theuerkauf A, Nicolay NH, Rühle A.   +13 more
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Causal effect of diabetes duration on productivity by socio-economic position in Germany between 2009 and 2021. [PDF]

Eur J Public Health
Mackowiak MM, Hoyer A, Piedboeuf-Potyka K, Neuhäuser M, Kuss O, Tönnies T.   +5 more
europepmc   +1 more source

Reluctance and determination: the prelude to the Austro-Hungarian occupation of Bosnia-Herzegovina in 1878 [PDF]

, 2015
Detrez, Raymond
core  

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

Advanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale, Luca Messina, Valeria Panzetta, Stefania Saporito, Costantino Menna, Maurizio Ventre, Paolo A. Netti   +6 more
wiley   +1 more source

Prevalence of schistosome infection among children under two years of age: a brief report from medium-to-high endemic regions of Schistosoma mansoni in Madagascar. [PDF]

Trop Med Health
Kislaya I, Rakotoarivelo RA, Rasamoelina T, Solonirina J, Brito A, Ratiaharison EF, Razafindrakoto R, Razafindralava NM, Rakotozandrindrainy N, Radomanana M, Andrianarivelo MR, Klein P, Jaeger A, Lorenz E, Hameister J, Hoekstra PT, Corstjens PLAM, Schwarz NG, van Dam GJ, May J, Marchese V, Rakotozandrindrainy R, Fusco D, freeBILy consortium.   +23 more
europepmc   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Spatial variation in risk factors for anti-hepatitis E antibody titers in a population-based German study. [PDF]

Sci Rep
Díaz AC, Ittermann T, Nauck M, Petersmann A, Völzke H, Schauer B.   +5 more
europepmc   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Depression, but Not Fatigue, Improves as Part of Multimodal Post-COVID Rehabilitation.

Psychother Psychosom
Kupferschmitt AA, Hinterberger T, Herrmann C, Jöbges M, Kelm S, Sütfels G, Loew TH, Köllner V.   +7 more
europepmc   +1 more source