Results 21 to 30 of about 215,077 (307)

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non‐coding RNA and synonymous mutations

EMBO Molecular Medicine, 2016
Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor‐specific mutations not only in protein‐coding ...
Sven Diederichs, Lorenz Bartsch, Julia C Berkmann, Karin Fröse, Jana Heitmann, Caroline Hoppe, Deetje Iggena, Danny Jazmati, Philipp Karschnia, Miriam Linsenmeier, Thomas Maulhardt, Lino Möhrmann, Johannes Morstein, Stella V Paffenholz, Paula Röpenack, Timo Rückert, Ludger Sandig, Maximilian Schell, Anna Steinmann, Gjendine Voss, Jacqueline Wasmuth, Maria E Weinberger, Ramona Wullenkord   +22 more
doaj   +1 more source

Efficacy of an internet-based self-management intervention for depression or dysthymia – a study protocol of an RCT using an active control condition

BMC Psychiatry, 2019
Background The treatment of major depressive disorder, a highly prevalent disorder associated with pronounced burden, is a large challenge to healthcare systems worldwide.
Caroline Oehler, Frauke Görges, Daniel Böttger, Juliane Hug, Nicole Koburger, Elisabeth Kohls, Christine Rummel-Kluge   +6 more
doaj   +1 more source

Restored TDCA and valine levels imitate the effects of bariatric surgery

eLife, 2021
Background: Obesity is widespread and linked to various co-morbidities. Bariatric surgery has been identified as the only effective treatment, promoting sustained weight loss and the remission of co-morbidities. Methods: Metabolic profiling was performed
Markus Quante, Jasper Iske, Timm Heinbokel, Bhavna N Desai, Hector Rodriguez Cetina Biefer, Yeqi Nian, Felix Krenzien, Tomohisa Matsunaga, Hirofumi Uehara, Ryoichi Maenosono, Haruhito Azuma, Johann Pratschke, Christine S Falk, Tammy Lo, Eric Sheu, Ali Tavakkoli, Reza Abdi, David Perkins, Maria-Luisa Alegre, Alexander S Banks, Hao Zhou, Abdallah Elkhal, Stefan G Tullius   +22 more
doaj   +1 more source

Air-water flows at hydraulic structures: Experimental investigations of interfacial characteristics and air-water mass transfer

, 2020
Air-water mass transfer in multiphase flows plays a key role in designing hydraulic structures. Air entrainment processes typically occur in spillways, drop shafts, stilling basins or in the casing of hydraulic impulse turbines.
Kramer, Matthias ; https://orcid.org/
core   +2 more sources

GET.HAPPY - Acceptance of an internet-based self-management positive psychology intervention for adult primary care patients with mild and moderate depression or dysthymia: A pilot study

Internet Interventions, 2018
Introduction: A growing number of internet interventions have been shown to help in alleviating symptoms of depression. So far, only little research has focused on other methods than CBT.
Frauke Görges, Caroline Oehler, Eckart von Hirschhausen, Ulrich Hegerl, Christine Rummel-Kluge   +4 more
doaj   +1 more source

Nematode-based indices in soil ecology: Application, utility, and future directions [PDF]

, 2022
14 Pág.The health and functioning of soil ecosystems are the foundation of sustainable food production and land management. Of key importance in achieving sustainability, is the frequent measurement of soil health, and indices based on the community ...
Fourie, Hendrika, Du Preez, Gerhard, De Goede, Ron, Daneel, Mieke, de Goede, R.G.M., Geisen, Stefan, Korthals, Gerard, Schmidt, Jan Henrik, Geisen, S.A., Ferris, Howard, Korthals, G.W., Kakouli-Duarte, Thomais, Du Toit, Marié Joey, Sánchez-Moreno, Sara   +13 more
core   +1 more source

Four-state ferroelectric spin-valve [PDF]

, 2015
This work is licensed under a Creative Commons Attribution 4.0 International License.Spin-valves had empowered the giant magnetoresistance (GMR) devices to have memory. The insertion of thin antiferromagnetic (AFM) films allowed two stable magnetic field-
Martí, Xavier, Pippel, Eckhard, Nicklin, Chris, Apachitei, Geanina, Ferrer, Pilar, Quindeau, Andy, Martí Rovirosa, Xavier, Fina, Ignasi, Alexe, Marin, Hesse, Dietrich   +9 more
core   +1 more source

Short fatigue crack growth in an artificial-defect-containing nanostructured bainitic steel

, 2023
For a full exploitation of novel steels in applications under mechanical cyclic loading, it is vital to understand the crack-microstructure interactions. In this work, the fatigue behaviour of a nanostructured bainitic steel in the short crack regime has
Lucia Morales-Rivas, Kerscher, Eberhard, Morales-Rivas, Lucía, Eberhard Kerscher, Ava Azadi, Azadi, Ava   +5 more
core   +1 more source

The Rationales of Open Science: Digitalisation and Democratisation in Research

, 2018
How can citizens best be involved in the scientific process, and how ‘Open’ can we make science? How do we ensure that the highest standards in scientific research are maintained in such a system?
German Research Foundation, Science Europe   +1 more
core   +1 more source

Selected Formal and Casual Correspondence between sociologists P.A. Sorokin and L. von Wiese (1950–1966). Transl. from Eng. and publication by N.A. Golovin

Социологический журнал, 2022
The postwar correspondence between P.A. Sorokin, head of the Harvard Centre for the Study of Creative Altruism, and L. von Wiese, President of the German Society for Sociology and publisher of a respected sociological journal from 1950 to 1966, describes
Nikolay A. Golovin
doaj   +1 more source