Results 131 to 140 of about 431,267 (267)

New Voices, New Perspectives

Africa Spectrum, 2020
Leonardo Arriola, Julia Grauvogel
doaj   +1 more source

AI Chatbot Answers for Drug Dosing Adjustments According to Renal Function in Geriatric Patients Using the New Scoring System (AI Quality Output Score): Cross-Sectional Study. [PDF]

JMIR AI
Barbonus C, Sultzer R, Bertsche T.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Stigma toward individuals with cannabis use disorder across age groups: associations with familiarity and sociodemographic characteristics. [PDF]

Harm Reduct J
Basedow LA, Wandinger E, Brindle A, Kölch M, Reis O.   +4 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Fine Particulate Exposure During Pregnancy Impacts on Perinatal Complications in Deeply Phenotyped Preterm Infants With Significant Immaturity. [PDF]

Pulm Circ
Johansson C, Kraus Y, Sanchez JDH, Schubert B, Wolf K, Voss C, Stoeger T, Seegmüller T, Flemmer AW, Förster K, Standl M, Hilgendorff A.   +11 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

ON THE STUDYING OF GERMAN TOPONYMS [PDF]

Вестник Башкирского университета, 2018
openaire   +1 more source

Prevalence and determinants of burnout among anaesthetists in Switzerland: A pooled analysis of two multicentre cross-sectional studies. [PDF]

Eur J Anaesthesiol Intensive Care
Gasciauskaite G, Braun J, Suppan M, Nöthiger CB, Savoldelli GL, Gisselbaek M.   +5 more
europepmc   +1 more source