Results 141 to 150 of about 56,332 (302)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

[News Clip: Crop food for Germans]

, 1953
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about citizens of Caldwell County raising money to donate thousands of pounds of flour to West Germany, to feed refugees from Communist East ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Presence of mucin droplets during endoscopic submucosal dissection at the submucosa and beyond. [PDF]

Endoscopy
Wong L, Pindozzi F, Muñoz-González R, Perelló C, Padron A, Benites-Goñi H, Uchima H.   +6 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Displacement of Germans from the region Liberec

, 2017
The bachelor thesis deals with the issue of the displacement of Germans from the Liberec region. The thesis describes the phases of displacements that took place in the territory of Liberec and what their cause was.
ČIHULOVÁ, Barbora
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Nuclear archaeology reassesses Heisenberg's last reactor experiment. [PDF]

PNAS Nexus
Park PJ, Robertson B, Hiebert ME, Zhao J, Sivels CB, Koeth TW.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Attitudes to Germans

Compilation of recordings containing memories of the First World War, from the collections of the East Midlands Oral History Archive. Memories of attitudes to Germans, the things families did to avoid being 'unpatriotic', Germans who ran shops or ...
Hyde, Colin
core  

Ozonation Eliminates Viable but Not Culturable <i>Legionella pneumophila</i> More Effectively than Chlorination. [PDF]

Pathogens
Arqué E, Simon-Coma M, Oliveras P, Reynaga EA, Sopena N, Pedro-Botet ML, Párraga-Niño N.   +6 more
europepmc   +1 more source