Results 191 to 200 of about 257,440 (310)

Refractory Generalised Morphea in Association with Reactive Hypereosinophil Syndrome Successfully Managed with Abatacept.

Indian J Dermatol
Lluch-Galcerá JJ, Casafont-Solé I, Xicoy B, Quer A, Bielsa I.   +4 more
europepmc   +1 more source

Erratum: [Erratum] Tofacitinib Improves Motor Symptoms in Parkinsonism Associated with a Heterozygous NGLY1 Variant and Autoimmune Disease. [PDF]

Eur J Case Rep Intern Med
Reina-Llompart N, Serrano-López S, Torres-Iglesias G, Álvarez-Troncoso J.   +3 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Universal Cytomegalovirus Screening in the First Trimester of Pregnancy: The Multicentre Observational Cohort Study in the Area of Barcelona (CITEMB Study). [PDF]

BJOG
Sánchez-Durán MÁ, Esperalba J, Scazzocchio E, Fernández-Torm I, Vázquez-Segura E, Gracia-Salazar O, Calveiro-Hermo M, Munrós-Feliu J, Francesch-Campi A, Alcoverro-Bedos L, Ribas-Tristany A, Del Viso-Lajara C, Mitjans-Carrasco J, Guerrero-Martínez M, Fernández-Rivas G, Zientalska AM, Liutsko L, Falguera-Puig G, Martínez-Bueno C, Maiz N, Gol R, CITEMB group.   +21 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Changing Prevalence of Immunocompromising Conditions in Patients Hospitalized with Severe Acute Respiratory Infection in Europe: Insights from the COVIDRIVE Study. [PDF]

J Epidemiol Glob Health
Meeraus W, Prokić I, Breugelmans JG, Chatzikonstantinidou K, Conde-Sousa E, Casas I, Hartig-Merkel W, Ten Kate GL, Manzanares-Laya S, Martin C, Orsi A, Romero SO, Venkatesan S, Widdowson MA, Bollaerts K, Taylor S.   +15 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Impact of Pulmonary Rehabilitation on Physical, Mental Health and Quality of Life in Children with Post-COVID-19 Condition: A 12-Month Quasi-Experimental Study. [PDF]

J Clin Med
Goicoechea-Calvo A, Navarro Expósito N, Coll-Fernández R, Colomer Giralt M, Martín Saavedra A, González-Aumatell A, Méndez-Hernández M, Carreras-Abad C, Moreira M, Giralt-López M, Pallarès N, Tebe Cordomi C, Rodríguez-Palmero A, Rodrigo C, Mata MJD.   +14 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Functional outcome, return to work and quality of life in patients with non-aneurysmal subarachnoid hemorrhage. [PDF]

Eur Stroke J
Dronkers WJ, Germans MR, Post R, Coert BA, Coutinho JM, van den Berg R, Vandertop WP.   +6 more
europepmc   +1 more source