Results 71 to 80 of about 49,142 (306)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Germans from Russia Heritage Society, Red River Chapter, Collection
Nineteen (19) scrapbooks containing correspondence, club materials, photographs, ephemera, and periodical clippings relating to the Germans from Russia Heritage Society, Red River Chapter, 1978- 2000. Club materials, ephemera, and photographs, circa 1985-
Germans from Russia Heritage Society
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
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The focus of this article lies on the importance of the pogroms of 1918-1919 for the memory of Central and Eastern European Jewry of the First World War and the retrospective perception of the various occupying powers. Exemplarily, the pogroms of Krakow,
Frank M. Schuster
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
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Many Northern and Western Europeans who seek a life that offers guaranteed weather, sea, sunshine, natural beauty, positive social relationships and other advantages are choosing to spend all or part of the year on the Aegean and Mediterranean coasts of ...
Bahar, Halil Ibrahim
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The article is based on a presentation made at the 1998 AHSGR convention in Wichita, Kansas at the time when Professor Mai was an Assistant Professor of Library Science at Purdue University.In the spring of 1766, amidst the turmoil of post-war Germany, a
Mai, Brent Alan, 1964-
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
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