Results 131 to 140 of about 1,450,985 (287)

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Rising Wage Dispersion, After All ! The German Wage Structure at the Turn of the Century [PDF]

Using register data from the IAB employment sample, this paper studies the wage structure in the German labor market throughout the years 1992{2001. Wage dispersion has generally been rising.
Kohn, Karsten
core  

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

Annals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji, Christian J. Rampal, Esteban C. Rodríguez, Virginie Petel Légaré, Alexandra Lissouba, Sabrina Semmler, Meijiang Liao, Jay P. Ross, Guy A. Rouleau, Christine Vande Velde, Gary A.B. Armstrong   +10 more
wiley   +1 more source

Forecasting Regional Employment in Germany by Means of Neural Networks and Genetic Algorithms [PDF]

The aim of this paper is to develop and apply Neural Network (NN) models in order to forecast regional employment patterns in Germany. NNs are statistical tools based on learning algorithms with a distribution over a large amount of quantitative data ...
Aura Reggiani, Peter Nijkamp, Roberto Patuelli, Simonetta Longhi   +3 more
core  

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

Ungesättigte Phosphor‐Elektrophile zur Untersuchung von Protein‐Tyrosin‐Phosphatasen

Angewandte Chemie, EarlyView.
Negativ geladene Aryl‐Ethynyl‐Phosphonamid‐ und Phosphonsäuren werden als reaktionsarme Elektrophile für peptidbasierte Aktivitätssonden eingeführt, die eine selektive, zielspezifische Profilierung von Protein‐Tyrosin‐Phosphatasen ermöglichen. Die Sonden zeigen keine Off‐Target‐Cystein‐Reaktivität und binden in der globalen Proteomanalyse nur an die ...
Eleftheria Poulou, Max Ruwolt, Christian E. Stieger, Kristin Kemnitz‐Hassanin, Christian P. R. Hackenberger   +4 more
wiley   +1 more source

Equivalence Scales for the Former West Germany [PDF]

Equivalence scales provide answers to questions like how much a household with four children needs to spend compared to a household with two children or how much a childless couple needs to spend compared to a single person household to attain the same ...
Charlier, E.
core   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Wages in the East German transition process: facts and explanations [PDF]

We analyze wage developments in the East German transition process both at the macro and at the microeconomic level. At the macroeconomic level, we draw special attention to the important distinction between product and consumption wages, describe the ...
Franz, Wolfgang, Steiner, Viktor
core  

Shrinkage Mitigation and Mechanical Properties of Cement‐Based Mortar With Silane‐Functionalized Hydrogels

Journal of Applied Polymer Science, EarlyView.
Schematic depiction of silane‐functionalized hydrogels utilized in this study along with chemical structures of the primary comonents (Acrylamide, N,N'‐methylenebisacrylamide, and 3‐(trimethoxysilyl) propyl methacrylate). ABSTRACT This study investigates the applications of silane‐loaded polymer hydrogels in field‐relevant cement‐based mortar intended ...
Daniel S. Hiller, Akul N. Seshadri, Christof Schröfl, Kendra A. Erk   +3 more
wiley   +1 more source