Results 91 to 100 of about 2,888,442 (218)

Abstract 14:25 VASCULARIZED LYMPH NODE TRANSFER FROM THE TERMINAL ILEUM FOR RECONSTRUCTION OF LYMPHATIC EXTREMITY DRAINAGE AS TREATMENT FOR SECONDARY CHRONIC LYMPHEDEMA

Plastic and Reconstructive Surgery, Global Open, 2018
Lukas Wellkamp, Pascal Kirchhoff, GERMANY   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Abstract 14.15 SUPERMICROSURGICAL TREATMENT OF PERSISTENT LYMPHORRHEA WITH RECONSTRUCTIVE LYMPHOVENOUS ANASTOMOSIS

Plastic and Reconstructive Surgery, Global Open, 2018
Lukas Wellkamp, Pascal Kirchhoff, GERMANY   +2 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Abstract 8.55 PRECLINICAL AND CLINICAL APPROACHES IN PERIPHERAL NERVE SURGERY

Plastic and Reconstructive Surgery, Global Open, 2018
Tim Kornfeld, Christine Radtke, GERMANY
doaj   +1 more source

Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study

Scandinavian Journal of Work, Environment & Health
OBJECTIVE: This study aimed to determine if there is an increased risk of incident cardiovascular diseases (CVD) resulting from cumulative night shift work in the German population-based Gutenberg Health Study (GHS).
Sylvia Jankowiak, Karin Rossnagel, Juliane Bauer, Andreas Schulz, Falk Liebers, Ute Latza, Karla Romero Starke, Andreas Seidler, Matthias Nübling, Merle Riechmann-Wolf, Stephan Letzel, Philipp Wild, Natalie Arnold, Manfred Beutel, Norbert Pfeiffer, Karl Lackner, Thomas Münzel, Alicia Schulze, Janice Hegewald   +18 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

GERMAN-ISRAEL RELATIONS IN THE CONTEXT OF THE MIDDLE EAST PEACE PROCESS PROBLEMS (2005 – 2014)

Вестник Кемеровского государственного университета, 2014
The subject of the article is that aspect of the Israeli Merkel government's foreign policy vector in Germany, which is associated with the search for a peaceful settlement in the Middle East.
M. V. Streletz
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source