Results 231 to 240 of about 3,120,902 (290)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Author Correction: Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects. [PDF]

Commun Med (Lond)
Ousdal OT, Argyelan M, Laroy M, Anand A, Bouckaert F, Camprodon JA, Cano M, Cardoner N, Dannlowski U, Dols A, Emsell L, Espinoza R, Hebbrecht K, Hurlemann R, Jorgensen M, Kiebs M, Kishimoto T, Narr KL, Nordanskog P, Opel N, Redlich R, Rhebergen D, Sartorius A, Schrijvers D, Sienaert P, Soriano-Mas C, Takamiya A, Ten Doesschate F, Tendolkar I, Urretavizcaya M, van Diermen L, van Eijndhoven P, van Wingen G, van Waarde J, Vandenbulcke M, Verdijk J, Wade BSC, Antoine Y, Brekke N, Prudic J, McClintock S, Kessler U, Bartsch H, Odegaard K, Haavik J, Hammar Å, Abbott C, Oltedal L.   +47 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Five seconds to safety: detecting and managing critical instability before structured handover in non-trauma patients. [PDF]

Scand J Trauma Resusc Emerg Med
Gröning I, Thies KC, Biermann H, Wasser C, Ostrowski S, Beißner C, Kumle B, Kümpers P, Bernhard M, Michael M.   +9 more
europepmc   +1 more source

Gorbachev and the forgotten democratic revolution in East Germany

Gianluca Falanga
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Factors influencing vaccination decisions in patients with inflammatory rheumatic and musculoskeletal disease: a qualitative approach. [PDF]

BMC Rheumatol
Suslow A, Lauer R, Kiltz U, Giehl C, Hellwig K, Oganowski T, Grüter T, Zacharopoulou M, Stallmach A, Franz A, Marschall U, Saam J, Schumacher C, Stock S, Simic D, Shukri A, Schlößler K, Otte IC, Vollmar HC, VAC-MAC consortium.   +19 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

International spread or local outbreak? Epidemiologic analyses of transmission patterns of NDM-1-producing <i>Klebsiella pneumoniae</i> based on genomic surveillance data, Germany, January 2022 to February 2023. [PDF]

Euro Surveill
Sandfort M, Eisfeld J, Hans JB, Reichert F, Said D, Fischer MA, Maechler F, Piening B, Buck H, Litzba N, Semmler T, Werner G, Eckmanns T, Pfennigwerth N, Gatermann S, Haller S, Generic IGS system development group.   +16 more
europepmc   +1 more source