Results 121 to 130 of about 124,208 (312)

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

open access: yesAdvanced Science, EarlyView.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li   +11 more
wiley   +1 more source

Germinabilidad y metabolismo antioxidante en semillas de Passiflora caerulea L. expuestas a estrés salino [PDF]

open access: yes, 2018
P. caerulea es la especie Passiflora con más amplia distribución en Argentina. Si bien es necesario implementar prácticas de cultivo para disminuir el impacto debido a su extracción indiscriminada, la información sobre cómo los factores ambientales ...
Causin, Humberto Fabio   +1 more
core  

Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production [PDF]

open access: yes, 2019
Although many recombinant proteins have been produced in seeds at high yields without adverse effects on the plant, endoplasmic reticulum (ER) stress and aberrant localization of endogenous or recombinant proteins have also been reported.
Arcalis, Elsa   +13 more
core   +2 more sources

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

open access: yesAdvanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen   +10 more
wiley   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

open access: yesAdvanced Science, EarlyView.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang   +15 more
wiley   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu   +13 more
wiley   +1 more source

More than symbioses : orchid ecology ; with examples from the Sydney Region [PDF]

open access: yes, 2013
The Orchidaceae are one of the largest and most diverse families of flowering plants. Orchids grow as terrestrial, lithophytic, epiphytic or climbing herbs but most orchids native to the Sydney Region can be placed in one of two categories.
Entwisle, Timothy J.   +2 more
core  

In Vitro Pollen Germination in Fountain Grass [PDF]

open access: yesHortScience, 1994
M. Hockenberry Meyer, D.B. White
openaire   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

open access: yesAdvanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song   +14 more
wiley   +1 more source

In vitro germination and propagation of Apocynum lancifolium Russanov, an endemic species in South Korea

open access: yesForest Science and Technology
Apocynum lancifolium Russanov is an endangered and ecologically important plant endemic to South Korea. However, neither the mass germination of Apocynum seeds nor the production of its plantlets using in vitro culture systems have been reported ...
Ye Joo Sol   +5 more
doaj   +1 more source

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