Results 161 to 170 of about 13,351 (224)

A new germline mutation, R600Q, within the coding region ofRET proto-oncogene: A rare polymorphism or a MEN 2 causing mutation? [PDF]

, 2000
Marie-Laure Sez, Agustı́n Ruiz, A. Cebri�n, Fernando Ortíz Morales, Mercedes Robledo, Guillermo Antiolo, Salud Borrego   +6 more
openalex   +1 more source

Novel germline mutation (300-305delAGTTGA) in the human MSH2 gene in hereditary non-polyposis colorectal cancer (HNPCC) [PDF]

, 2000
Sabine Glasl, L. Papatheodorou, Gustavo Baretton, Ch. Jung, M Gross   +4 more
openalex   +1 more source

Differential responses to taxanes and PARP inhibitors in ATM‐ versus BRCA2‐mutated metastatic castrate‐resistant prostate cancer

The Prostate, Volume 83, Issue 3, Page 227-236, February 15, 2023., 2023
Abstract Background PARP (poly(ADP‐ribose) polymerase) inhibitors (PARPi) are now standard of care in metastatic castrate‐resistant prostate cancer (mCRPC) patients with select mutations in DNA damage repair (DDR) pathways, but patients with ATM‐ and BRCA2 mutations may respond differently to PARPi.
Christopher T. Su, Emily Nizialek, Jacob E. Berchuck, Panagiotis J. Vlachostergios, Ryan Ashkar, Alexandra Sokolova, Pedro C. Barata, Rahul R. Aggarwal, Rana R. McKay, Neeraj Agarwal, Heather M. McClure, Nellie Nafissi, Alan H. Bryce, Oliver Sartor, Nicolas Sayegh, Heather H. Cheng, Nabil Adra, Cora N. Sternberg, Mary‐Ellen Taplin, Marcin Cieslik, Ajjai S. Alva, Emmanuel S. Antonarakis   +21 more
wiley   +1 more source

ATM-Heterozygous Germline Mutations Contribute to Breast Cancer–Susceptibility

, 2000
Annegien Broeks, Jos Urbanus, Arno Floore, Ellen C. Dahler, Jan G.M. Klijn, Emiel J. Rutgers, Peter Devilee, Nicola S. Russell, Flora E. van Leeuwen, Laura J. van’t Veer   +9 more
openalex   +1 more source

Germline-Activating Mutation in the Kinase Domain of KIT Gene in Familial Gastrointestinal Stromal Tumors

, 2000
Koji Isozaki, Benoît Terris, Jacques Belghiti, Serge N. Schiffmann, Seiichi Hirota, Jean‐Marie Vanderwinden   +5 more
openalex   +1 more source

Discovery of germline and somatic mutations in apparently sporadic parathyroid tumours [PDF]

, 2000
S. Uchino, Shiro Noguchi, Mari Sato, Hiroyuki Yamashita, Hiroyuki Yamashita, Shin Watanabe, Akira Ohshima, M. Nagatomo, Mitsuo Adachi   +8 more
openalex   +1 more source

Germline Mutations in BMPR1A/ALK3 Cause a Subset of Cases of Juvenile Polyposis Syndrome and of Cowden and Bannayan-Riley-Ruvalcaba Syndromes* [PDF]

, 2001
Xiaoping Zhou, K Woodford-Richens, Rainer Lehtonen, Keisuke Kurose, Micheala A. Aldred, Heather Hampel, Virpi Launonen, Sanno Virta, Robert Pilarski, Reijo Salovaara, Walter F. Bodmer, Beth A. Conrad, Malcolm G. Dunlop, Shirley V. Hodgson, Takeo Iwama∥, Heikki Järvinen, Ilmo Kellokumpu, J‐H Kim, Barbara Leggett, David Markie, Jukka‐Pekka Mecklin, Kay Neale, Robin Phillips, J Piris, Paul Rozen, Richard S. Houlston, Lauri A. Aaltonen, Ian Tomlinson, Charis Eng   +28 more
openalex   +1 more source

Detection of germline BRCA1 mutations by Multiple-Dye Cleavase Fragment Length Polymorphism (MD-CFLP) method [PDF]

, 2001
Silvia Casadei, Laura Cortesi, Valeria Pensotti, Paolo Radice, Marco A. Pierotti, D. Amadori, Daniele Calistri   +6 more
openalex   +1 more source

Familial gastrointestinal stromal tumor with hyperpigmentation: Association with a germline mutation of the c-kit gene [PDF]

, 2001
Hironobu Maeyama, Eiko Hidaka, Hiroyoshi Ota, Satoshi Minami, M. Kajiyama, Akira Kuraishi, Hiromitsu Mori, Yoshiaki Matsuda, Shuichi Wada, Harutsugu Sodeyama, Shinji Nakata, Nobuyuki Kawamura, Satoru Hata, Masahide Watanabe, Yoshihiro Iijima, Tsutomu Katsuyama   +15 more
openalex   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source