Results 191 to 200 of about 618,513 (311)

Metabolic and Reproductive Responses to Peripartum Feed Supplementation in Hyperprolific Gilts. [PDF]

Life (Basel)
Cantin J, Cantin C, Mitjana O, Tejedor MT, Gil-Rubio C, Garrido AM, Falceto MV.   +6 more
europepmc   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Dams fed diet with no or minimal amounts of carbohydrates during pregnancy and lactation produce normal and healthy puppies: seven case reports. [PDF]

Front Vet Sci
Anturaniemi J, Moore R, Holm S, Hielm-Björkman A.   +3 more
europepmc   +1 more source

Length of Gestation Period in Dairy Cattle [PDF]

, 1953
Carson, James L.
core   +2 more sources

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Dietary Protein Level in Late Gestation: Effects on Nutritional and Developmental Responses in Jennies and Their Foals. [PDF]

Animals (Basel)
Guo Y, Li J, Shen Y, Yan S, Shi B, Zhao Y, Guo X.   +6 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Yolk sac development in dogs: from morphology to functional aspects. [PDF]

Anim Reprod
da Silva CGB, Greghi JR, Pontes MFF, Cardoso GS, Martins MIM, Ambrósio CE, Favaron PO.   +6 more
europepmc   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Severe Cord Entanglement in a Monochorionic-Monoamniotic Twin Pregnancy: Highlighting Perinatal Risks and Management Challenges-A Case Report. [PDF]

Case Rep Obstet Gynecol
Alagha M, Saroufine K, Aji H, Nabbout G.
europepmc   +1 more source