Results 91 to 100 of about 1,409,358 (284)

Factor V Leiden Mutation and its Impact on Pregnancy Complications

Acta Medica, 2011
Objective: The aim of this prospective study was to find the association between the factor V Leiden mutation and adverse pregnancy outcomes. Methods: This study is an analysis of a prospective observational study of the frequency of placenta-mediated ...
Ľubica Hammerová, Ján Chabada, Juraj Drobný, Angelika Bátorová   +3 more
doaj   +1 more source

ABSOLUTE UTERINE-FACTOR INFERTILITY - GESTATIONAL CARRIER OR UTERINE TRANSPLANT? – A COST EFFECTIVENESS ANALYSIS [PDF]

, 2023
Joshua C. Combs, M. Yamasaki, Kiley Hunkler, Jaime A. Roura-Monllor, Micah J. Hill, Alan H. DeCherney, Kathleen Devine, Robert J. Stillman, Jeanne E. O’Brien   +8 more
openalex   +1 more source

Methanol and isopropanol embryo dosage response curves for wild-type and ethanol-sensitive zebrafish [PDF]

, 2016
It is well established that ethanol has an array of negative effects on developing embryos, from craniofacial abnormalities to cognitive deficits and behavioral disorders.
Anderson, Ashley
core   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Screening for abdominal aortic aneurysm [PDF]

, 2009
The official published version can be found at the link ...
Buxton, MJ
core   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

The pregnancy outcome in patients with minor β-thalassemia [PDF]

Iranian Journal of Reproductive Medicine, 2011
Background: β-thalassemia is the most common hereditary disease in Iran and more than 2 million carriers of the β-thalassemia mutant gene are living in this country.Objective: To determine pregnancy outcome of women with β-thalassemia minor.Materials and
Mehran Karimi, Jamileh Jahanbakhsh, Alamtaj Samsami, Sedigheh Amooee   +3 more
doaj  

Maternal HBsAg carriers and pregnancy outcomes: a retrospective cohort analysis of 85,190 pregnancies

BMC Pregnancy and Childbirth, 2020
Background Nowadays, a positive HBV carrier status is common among pregnant women, especially in endemic areas (such as China), little is known about the impact of maternal HBV infection on the risk of adverse pregnancy outcomes.
Yulong Zhang, Jiacheng Chen, Tingting Liao, Siwen Chen, Jianying Yan, Xiaoqian Lin   +5 more
semanticscholar   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

A Comprehensive Cohort Analysis Comparing Growth and GH Therapy Response in IGF1R Mutation Carriers and SGA Children.

Journal of Clinical Endocrinology and Metabolism, 2020
CONTEXT IGF1 receptor mutations (IGF1RM) are rare; however, patients exhibit pronounced growth retardation without catch-up. Although several case reports exist, a comprehensive statistical analysis investigating growth profile and benefit of recombinant
E. Göpel, D. Rockstroh, Heike Pfäffle, M. Schlicke, S. B. Pozza, M. Gannagé-Yared, Z. Gucev, A. Mohn, Eva-Maria Harmel, J. Volkmann, Susann Weihrauch-Blüher, R. Gausche, H. Bogatsch, Christoph Beger, J. Klammt, R. Pfäffle   +15 more
semanticscholar   +1 more source