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Gestational Trophoblastic Neoplasia
Obstetrics and Gynecology Clinics of North America, 2012Trophoblastic neoplasms are a truly fascinating set of diseases that arise from a failed gestation. A molar pregnancy is an allograft of fetal tissue typically containing only paternal chromosomes that may invade the maternal decidua following a failed gestation that may have arisen up to decades earlier.
R, Osborne, J, Dodge
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GESTATIONAL TROPHOBLASTIC NEOPLASIA
Clinical Obstetrics and Gynecology, 1974This review covers the development of chemotherapeutic treatment during the past 25 years for gestational trophoblastic neoplasia; there is now a cure rate of 80% of the cases of hydatiform mole invasive mole and choriocarcinoma. The clinician pathologist investigator will have the prime role in future breakthroughs as he has had in the preceeding ...
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Gestational trophoblastic neoplasia
Seminars in Oncology Nursing, 1990Gestational trophoblastic neoplasia (GTN) constitutes a spectrum of benign and malignant diseases that are associated with conception. The majority of patients with a benign GTN (hydatidiform mole) spontaneously enter remission after evacuation; however, 15% to 20% will develop a malignant form of GTN.
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Gestational trophoblastic neoplasia
2011Abstract Arising from the cells of conception, gestational trophoblastic disease (GTD) forms a spectrum of disorders from the premalignant complete and partial hydatidiform moles through to the malignant invasive mole, choriocarcinoma and very rare placental site trophoblastic tumours (PSTT).
Philip Savage, Michael J. Seckl
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Gestational Trophoblastic Neoplasia
Hospital Practice, 1972The chorionic gonadotropin titer now makes it possible to identify early those postmolar patients who are likely to progress to choriocarcinoma, thereby opening the way to definitive treatment of this highly lethal condition. Complete and sustained remission can now be achieved in 90% of patients in whom appropriate chemotherapy is begun within four ...
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Gestational Trophoblastic Neoplasia
2015The pathologic classification and histologic findings of gestational trophoblastic neoplasia are discussed.
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Gestational trophoblastic neoplasia: an update
Current Oncology Reports, 2008Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, and placental site trophoblastic tumors. The overall cure rate in treating these tumors currently exceeds 90%. Thorough evaluation and staging allow selection of appropriate therapy that maximizes chances for cure while minimizing toxicity.
Jacqueline M, Morgan, John R, Lurain
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Management of Gestational Trophoblastic Neoplasia
Seminars in Oncology, 2009Molar pregnancy and gestational trophoblastic neoplasms (GTN) comprise a group of interrelated diseases with a varying degree of aggressiveness. Complete and partial molar pregnancy, invasive mole, placental site trophoblastic tumor (PSTT), and choriocarcinoma cover the spectrum of GTN.
Neil S, Horowitz +2 more
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Radiology of gestational trophoblastic neoplasia
Clinical Radiology, 2006Gestational trophoblastic neoplasia (GTN) encompasses a broad spectrum of placental lesions from the pre-malignant hydatidiform mole (complete and partial) through to the malignant invasive mole, choriocarcinoma and rare placental site trophoblastic tumour (PSTT). Ultrasound remains the radiological investigation of choice for initial diagnosis, and it
S D, Allen +4 more
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HYPERTHYROIDISM IN GESTATIONAL TROPHOBLASTIC NEOPLASIA
Clinical Endocrinology, 1981SUMMARYThe thyroid status of twenty‐seven African patients with gestational trophoblastic neoplasia (GTN) was studied. Fifteen patients were found to be biochemically hyperthyroid (eight patients with choriocarcinoma; seven with hydatidiform mole). Of these fifteen patients, nine were clinically thyrotoxic.
R J, Norman +5 more
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