Results 71 to 80 of about 53,640 (266)

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

Advanced Science, EarlyView.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed, Carl E. Eskildsen, Luca Panariello, André Shamsabadi, Christy J. Sadler, Edmund H. Wilkes, Federico Galvanin, Yuxi Cheng, Sara Carvalho, Srdjan Saso, Molly M. Stevens   +10 more
wiley   +1 more source

Gestational weight gain during pregnancy and its determinants: A longitudinal study

Caspian Journal of Reproductive Medicine, 2018
Background: Gestational weight gain during pregnancy is supposedly associated with the increased risk of some adverse outcomes. Thus, assessing the trend of gestational weight gain and its associated risk factors for each population may reduce the ...
Moein Yoosefi, Azin Khosrovirad, Seyed Hossein Seyed Agha, Lalaeh Zand Parsa, Negar Rezaei, Mahmood Bakhtiyari, Farid Zayeri   +6 more
doaj  

Association between sleep quality and weight gain in pregnancy: a cross-sectional study

BMC Pregnancy and Childbirth
Introduction There are grounds for the hypothesis that poor sleep quality, regardless of the pre-gestational nutritional status, is a risk factor for inadequate gestational weight gain.
Ana Paula Santos Costa Roberto, Ana Beatriz Henrique Parenti, Caroline de Barros Gomes, Maria Antonieta de Barros Leite Carvalhaes, Cristina Maria Garcia de Lima Parada   +4 more
doaj   +1 more source

Factors associated with fetal macrosomia

Revista de Saúde Pública, 2019
OBJECTIVE To evaluate the clinical factors, as well as weight gain, in a group of pregnant women, associating them with fetal macrosomia in a public institution in Antioquia, Colombia, from 2010-2017.
Vanessa Agudelo-Espitia, Beatriz Elena Parra-Sosa, Sandra L Restrepo-Mesa   +2 more
doaj   +2 more sources

Personality type influence the gestational weight gain

Gynecological Endocrinology, 2017
Pregnancy is frequently followed by the development of obesity. Aside from psychological factors, hormonal changes influence weight gain in pregnant women. We attempted to assess the potential association between personality type and the extent of gestational weight gain.
Grzegorz, Franik, Nela, Lipka, Katarzyna, Kopyto, Joanna, Kopocińska, Aleksander, Owczarek, Jerzy, Sikora, Paweł, Madej, Jerzy, Chudek, Magdalena, Olszanecka-Glinianowicz   +8 more
openaire   +2 more sources

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

GESTATIONAL WEIGHT GAIN DEPENDS ON THE INITIAL ANTHROPOMETRIC VALUES

Акушерство, гинекология и репродукция, 2017
The aim was to study whether the increase in body weight during pregnancy depends on the initial anthropometric values. Materials and methods. This prospective study included 100 pregnant women; the measurements of their height, body weight, and BMI were
N. B. Chabanova, T. N. Vasilkova, T. P. Shevlyukova   +2 more
doaj   +1 more source

Livestock Tango: U.S. and Latin America Dance Together, but Who Will Lead?

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study examines the competitiveness between Latin American and U.S. livestock and meat sectors. We employ a computable general equilibrium modeling framework to evaluate two scenarios: coordinated improvements in Latin American productivity, transport efficiency, and market access (Scenario I), and the minimum productivity gains required ...
Taís C. Menezes, Amanda M. Countryman, Dustin L. Pendell   +2 more
wiley   +1 more source