Results 31 to 40 of about 99,215 (273)

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

Angewandte Chemie International Edition, EarlyView.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp, Quentin Bertrand, Matilde Trabuco, Anna Duran‐Corbera, Maria Tindara Ignazzitto, Hannah Glover, Fabienne Stierli, Juanlo Catena, Melissa Carrillo, Sina Hartmann, Hans‐Peter Seidel, Matthias Mulder, Thomas Mason, Yasushi Kondo, Maximillian Wranik, Martin Appleby, Christoph Sager, Raymond Sierra, Gregory Gate, Pamela Schleissner, Xinxin Cheng, Tobias Weinert, Robert Cheng, Sandra Mous, John H. Beale, Michal Kepa, Amadeu Llebaria, Michael Hennig, Xavier Rovira, Joerg Standfuss   +29 more
wiley   +1 more source

Under the Shade of a Coolabah Tree: A Second Cache of Tulas From the Boulia District, Western Queensland

Archaeology in Oceania, EarlyView.
ABSTRACT This paper reports on the excavation of a cache of stone artefacts, buried on the bank of a waterhole or ‘billabong’ in central western Queensland. This is an extremely rare find, and yet it is the second such site to be reported within less than a 10 km radius.
Yinika L. Perston, Lynley A. Wallis, Heather Burke, Lorna Bogdanek, Trevina Rogers, Justine Kemp   +5 more
wiley   +1 more source

Sustainability and Earnings Quality: The Moderating Role of Institutional Factors

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The objective of this paper is to examine the impact of firms' sustainability performance on earnings quality, with a particular focus on the moderating role of institutional factors in Latin American countries for the period 2012–2023. A panel data set with 390 companies was structured with information sourced from the London Stock Exchange ...
Juan F. Garrido Navia, Jesus Ancizar Gomez Daza, Julian Benavides, David Urbano   +3 more
wiley   +1 more source

Institutionalizing Advisory Bodies in Climate Governance: Between Transparency, Accountability and Efficiency

Environmental Policy and Governance, EarlyView.
ABSTRACT The implementation of effective climate governance increasingly relies on advisory bodies that monitor the effectiveness of policies and management mechanisms. Despite their strategic importance to institutionalizing climate governance, limited attention has been paid to the roles, trajectories, and effectiveness of these advisory bodies ...
David Talbot, Luc Bernier
wiley   +1 more source

Do Institutions Make Street‐Level Bureaucrats Prosocial? Agent‐Based Evidence Shows That New Public Management Does Not

European Policy Analysis, EarlyView.
ABSTRACT Does street‐level bureaucrats' (SLBs) willingness to sacrifice their own self‐interests to meet the needs of their clients vary depending on their contexts? To date, it has been very challenging to empirically examine how SLBs who have different orientations toward social values might act in different institutional and administrative contexts.
Nissim Cohen, Teddy Lazebnik
wiley   +1 more source

Gérer durablement les plantations forestières : des critères et des indicateurs [fiches de compétences forêts SIA 2011] [PDF]

, 2011
Les fonctions écologiques, économiques et sociales des forêts naturelles font l'objet de législations et de Principes, critères, indicateurs et vérificateurs (PCIV) de gestion durable.
Marien, Jean-Noël
core  

Assessing Spatio-Temporal Hydrological Impacts of Climate Change in the Siliana Watershed, Northwestern Tunisia

Atmosphere
Climate change is one of the most critical factors impacting hydrological dynamic systems. This study investigated how climate change influences the hydrological dynamics within the Siliana watershed in northwestern Tunisia, employing the Soil and Water ...
Imen El Ghoul, Haykel Sellami, Slaheddine Khlifi, Marnik Vanclooster   +3 more
doaj   +1 more source

SAVOIRS ENDOGENES ET PRATIQUES COMMUNAUTAIRES EN LIEN AVEC LA PROTECTION ET L’EROSION DE LA BIODIVERSITE DANS LA PROVINCE DU NORD-UBANGI [PDF]

Ziglôbitha
Résumé : Le présent article décrit et analyse les savoirs endogènes et les pratiques communautaires Ngbaka et Ngbandi en lien avec la protection et l’érosion de la biodiversité afin de proposer une piste pour une gestion durable des ressources naturelles.
Philippe GBAGALA NDAGI
doaj   +1 more source

Gestion patrimoniale, gestion durable des ressources et évaluation

Politiques et management public, 1994
On utilise souvent de facon indifferenciee les concepts de patrimoine, de ressources durables, de qualite des milieux naturels ou des milieux de vie pour penser les particularites de la gestion de l'environnement, des monuments, des œuvres d'art et d'autres temoignages du passe, mais aussi de ressources non renouvelables.
openaire   +2 more sources

Evaluation environnementale et choix de stratégies durables de gestion des risques naturels [PDF]

, 2013
International audienceDevenus une référence suite à la Déclaration de Rio (1992), les principes du développement durable ont entrainé une modification des pratiques décisionnelles dans plusieurs domaines, dont celui de la gestion des risques naturels et ...
AL HEIB, Marwan, Deck, Olivier, Edjossan-Sossou, Abla-M., Verdel, Thierry   +3 more
core   +1 more source