Results 71 to 80 of about 9,632 (295)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Move, Hold and Touch: A Framework for Tangible Gesture Interactive Systems

open access: yesMachines, 2015
Technology is spreading in our everyday world, and digital interaction beyond the screen, with real objects, allows taking advantage of our natural manipulative and communicative skills.
Leonardo Angelini   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Real-Time Pinch-to-Zoom Motion Detection by Means of a Surface EMG-Based Human-Computer Interface

open access: yesSensors, 2014
In this paper, we propose a system for inferring the pinch-to-zoom gesture using surface EMG (Electromyography) signals in real time. Pinch-to-zoom, which is a common gesture in smart devices such as an iPhone or an Android phone, is used to control the ...
Jongin Kim   +3 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Gestural Interaction Using Feature Classification

open access: yes, 2008
This paper describes our ongoing research work on deviceless interaction using hand gesture recognition with a calibrated stereo system. Video-based interaction is one of the most intuitive kinds of Human-Computer-Interaction with Virtual-Reality applications due to the fact that users are not wired to a computer.
openaire   +1 more source

3D Hand Gesture Recognition using the Hough Transform

open access: yesAdvances in Electrical and Computer Engineering, 2013
This paper presents an automatic 3D dynamic hand gesture recognition algorithm relying on both intensity and depth information provided by a Kinect camera.
OPRISESCU, S., BARTH, E.
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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