Results 51 to 60 of about 444,579 (327)
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
The relation between pitch and gestures in a story-telling task [PDF]
Anecdotal evidence suggests that both pitch range and gestures contribute to the perception of speakers\u2019 liveliness in speech. However, the relation between speakers\u2019 pitch range and gestures has received little attention.
Brugnerotto, S., Busa', MARIA GRAZIA
core
Investigating Machine Learning Techniques for Gesture Recognition with Low-Cost Capacitive Sensing Arrays [PDF]
Machine learning has proven to be an effective tool for forming models to make predictions based on sample data. Supervised learning, a subset of machine learning, can be used to map input data to output labels based on pre-existing paired data. Datasets
Fahr Jr., Michael
core +2 more sources
Evidence from adult studies of deaf signers supports the dissociation between neural systems involved in processing visual linguistic and non-linguistic body actions. The question of how and when this specialization arises is poorly understood.
Rain G. Bosworth+2 more
doaj +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Most language functions are under the dominance of the left cerebral hemisphere and involve a complex neural network in which some cerebral regions play a key-role such as Broca’s and Wernicke's areas within the frontal and the temporal lobes ...
Adrien Meguerditchian+3 more
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Vision-based hand gesture interaction using particle filter, principle component analysis and transition network [PDF]
Vision-based human-computer interaction is becoming important nowadays. It offers natural interaction with computers and frees users from mechanical interaction devices, which is favourable especially for wearable computers.
Sun, Y, Wang, F, Wang, Z, Zhang, Z
core +1 more source