Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Student diversity, extra-curricular activities and perceptions of graduate outcomes [PDF]
This research will examine how different student groups engage with extra-curricular activities and what effect these activities have on their degree and graduate outcomes.
Lido, Catherine +3 more
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Report on the first phase of the study on men’s usage of the Bradford Health of Men services [PDF]
This is a summary of the full report on the first year of the HOM project in Bradford, published in March 2005 and available at www.healthofmen.com . In this summary there is a concentration on three things, the background to the project, the experiences
Cash, K, White, AK
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Internet and Civic Engagement [PDF]
Based on a survey, analyzes how socioeconomic status and other demographics correlate with online and offline political and civic engagement.
Aaron Smith +3 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Getting Engaged: Program and Event Planning for Clients with Diverse Abilities
For event planners, it is important to be inclusive of people with diverse physical and mental abilities when establishing accommodations for programs or events.
Kathryn A. Stofer
doaj
Bisinis belong olgeta mere long Honiara, Solomon Islands = Informal activities of the women of Honiara, Solomon Islands : 31.798 research project presented in partial fulfilment of the requirements of the Degree of Master of Philosophy in Development Studies at Massey University [PDF]
Solomon Islands' women in the Urban Informal Sector (UIS) seem to be invisible to the policy makers both from the perspective of their contribution and their needs. Although government programs aim at assisting small scale entrepreneurs, women as a group
Fakaia, Matthew
core
Working out abjection in the Panapompom bêche-de-mer fishery: Race, economic change and the future in Papua New Guinea [PDF]
This is the accepted version of the following article: Rollason, W. (2010), Working out abjection in the Panapompom bêche-de-mer fishery: Race, economic change and the future in Papua New Guinea. The Australian Journal of Anthropology, 21: 149–170. doi:
Althusser +93 more
core +1 more source

