Results 131 to 140 of about 103,707 (261)

Nephrological perspectives on the underutilization of SGLT2is in heart failure and chronic kidney disease

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1490-1491, April 2025.
Özant Helvacı   +4 more
wiley   +1 more source

Hyperhomocysteinemia and Vitamin B Deficiency as Potential Aggravating Factors in Huntington's Disease: A Prospective Monocentric Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Although not confirmed, some studies have suggested that elevated homocysteine levels are common in patients with Huntington's disease (HD). Its clinical relevance remains unclear. Objectives We aimed to assess vitamin B and homocysteine levels in HD patients and explore the relationships among hyperhomocysteinemia, vitamin B ...
Salomé Puisieux   +16 more
wiley   +1 more source

GFR meets mTOR. Value of different methods to measure and estimate GFR & (Side) effects of mTOR inhibition in renal transplantation [PDF]

open access: yes, 2011
The subject of this thesis is twofold: where GFR and mTOR meet. Precise measurement of kidney function is difficult and cumbersome and many, simpler alternatives have been developed to determine GFR.
Baas, M.C., Baas, Marije C.
core  

Architectural Tailoring and Reinforcement Strategies for Improved Bearing Strength in Thick Carbon Fiber/Epoxy Laminates

open access: yesPolymer Composites, EarlyView.
Schematic overview of the investigated laminate architectures and reinforcement strategies used to evaluate their effects on the bearing performance and failure behaviour of thick carbon fibre/epoxy laminates. ABSTRACT This study provides a unified experimental comparison of 11 joint configurations in thick (7–12 mm) vacuum‐infused CFRP laminates ...
Hasan Caglar   +7 more
wiley   +1 more source

Performance of the estimated glomerular filtration rate creatinine and cystatin C based equations in Thai patients with chronic glomerulonephritis

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2015
Bancha Satirapoj, Ketkan Jirawatsiwaporn, Theerasak Tangwonglert, Panbubpa ChoovichianDivision of Nephrology, Department of Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, ThailandBackground: Glomerular filtration rate (GFR) is ...
Satirapoj B   +3 more
doaj  

An extinction‐emergency metacollection: Maximising future recovery options for Rhodomyrtus psidioides (Myrtaceae), threatened by Myrtle Rust

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
A challenge for wild plant conservation is the rising incidence of plant pathogens that are difficult to interdict, contain and manage. Invasive, fast‐moving, broad‐spectrum pathogens impose societal costs through losses of intrinsically valuable wild biodiversity, ecosystem function, current and potential genetic and biological assets, culturally ...
Robert O. Makinson   +7 more
wiley   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen   +6 more
wiley   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola   +9 more
wiley   +1 more source

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina   +2 more
wiley   +1 more source

Intersection of systemic lupus erythematosus and autoimmune thyroid disease: Shared pathophysiology, epidemiology, diagnosis, and management

open access: yesRheumatology &Autoimmunity, EarlyView.
A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa   +3 more
wiley   +1 more source

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