Results 221 to 230 of about 147,929 (284)

Phenotyping of Fontan‐Associated Renal Physiology and Disease

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
In patients with a Fontan circulation, both kidney function and glomerular injury progressively decline with age, with a stronger decline than in healthy individuals. Additionally, intrarenal haemodynamics in patients with a Fontan circulation demonstrate decreased venous and arterial compliance, evident through elevated venous impedance and renal ...
Gaston van Hassel   +7 more
wiley   +1 more source

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 928-941, April 2026.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

open access: yes
Transfusion, EarlyView.
Thane Kubik   +2 more
wiley   +1 more source

An IQ Consortium Perspective on the FDA Guidance for Assessment of Pharmacokinetics in Participants With Impaired Renal Function

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 838-845, April 2026.
The FDA published guidance on assessing pharmacokinetics (PK) in participants with impaired renal function in 2024. The IQ CPLG Organ Impairment Working Group summarized the industry’s perspective on this guidance by highlighting a few key updates in the 2024 guidance, including: (1) the recommendation of using estimated glomerular filtration rate ...
Yan Jin   +13 more
wiley   +1 more source

SGLT2 Inhibitors and Long-Term Outcomes After AKI. [PDF]

open access: yesKidney Int Rep
Wannakittirat A   +9 more
europepmc   +1 more source

Renal Adverse Events Associated With Ibuprofen Treatment After Hip and Knee Arthroplasties—A Protocol for the Preplanned Substudy of the PERISAFE Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 4, April 2026.
ABSTRACT Introduction Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for postoperative pain management after hip and knee arthroplasties but have been associated with renal adverse effects. The risk may increase when NSAIDs are combined with diuretics and angiotensin converting enzyme (ACE) inhibitors or Angiotensin‐II‐receptor ...
Christina Cleveland Westerdahl Laursen   +21 more
wiley   +1 more source

Preventive Effect of Powder Bergamot Juice (Citrus bergamia Risso & Poiteau) on Pathophysiological Processes of Renal Disease in an Experimental Western Diet Model. [PDF]

open access: yesMol Nutr Food Res
Santos MPSD   +10 more
europepmc   +1 more source

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