Phenotyping of Fontan‐Associated Renal Physiology and Disease
In patients with a Fontan circulation, both kidney function and glomerular injury progressively decline with age, with a stronger decline than in healthy individuals. Additionally, intrarenal haemodynamics in patients with a Fontan circulation demonstrate decreased venous and arterial compliance, evident through elevated venous impedance and renal ...
Gaston van Hassel +7 more
wiley +1 more source
Comparison of Creatinine-, Cystatin C-, and Combined Creatinine-Cystatin C-Based Equations for Estimating Glomerular Filtration Rate: A Real-World Analysis in Patients with Chronic Kidney Disease. [PDF]
Osredkar J +4 more
europepmc +1 more source
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park +22 more
wiley +1 more source
Can Variations in the Diet Quality Index Over Five Years Improve Renal Function and Lipid Profiles Among Patients with Type 2 Diabetes Mellitus? Results from the Prospective Azar Cohort Study. [PDF]
Asl ZS +5 more
europepmc +1 more source
Manufacturing and clinical applications of non‐CAR‐T immune effector cells
Transfusion, EarlyView.
Thane Kubik +2 more
wiley +1 more source
The FDA published guidance on assessing pharmacokinetics (PK) in participants with impaired renal function in 2024. The IQ CPLG Organ Impairment Working Group summarized the industry’s perspective on this guidance by highlighting a few key updates in the 2024 guidance, including: (1) the recommendation of using estimated glomerular filtration rate ...
Yan Jin +13 more
wiley +1 more source
SGLT2 Inhibitors and Long-Term Outcomes After AKI. [PDF]
Wannakittirat A +9 more
europepmc +1 more source
ABSTRACT Introduction Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for postoperative pain management after hip and knee arthroplasties but have been associated with renal adverse effects. The risk may increase when NSAIDs are combined with diuretics and angiotensin converting enzyme (ACE) inhibitors or Angiotensin‐II‐receptor ...
Christina Cleveland Westerdahl Laursen +21 more
wiley +1 more source
Preventive Effect of Powder Bergamot Juice (Citrus bergamia Risso & Poiteau) on Pathophysiological Processes of Renal Disease in an Experimental Western Diet Model. [PDF]
Santos MPSD +10 more
europepmc +1 more source
End points for sickle cell disease clinical trials: Renal and cardiopulmonary, cure, and low-resource settings [PDF]
al., et +2 more
core +1 more source

