Results 191 to 200 of about 4,957,958 (288)

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

open access: yesBrain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen   +8 more
wiley   +1 more source

Artificial intelligence–based 3D segmentation of tangle‐associated TDP‐43 in neurodegeneration

open access: yesBrain Pathology, EarlyView.
Multiplex immunostaining of anti‐phosphorylated TDP‐43, tau (AT8, pS396, TauC3, MN423, GT38), and Thioflavin S combined with AI‐based object recognition, reconstruction, and TAT maturation analysis pipeline in limbic regions revealed that distinct aggregation and tangle maturation patterns underscored region‐specific dynamics in the neurodegenerative ...
Gokhan Uruk   +6 more
wiley   +1 more source

Ghost sign for Duraflex Shoes on Grosvenor Street, 2024.

open access: yes
Ghost sign with severe deterioration. Based on other entries in our collection, this ghost sign previously advertised Duraflex Shoes, 'Shoes For Ladies'. In the background, there is a secondary ghost sign for Duraflex Shoes and 'J.H. Clarke & Co.
Hyde, Colin
core  

Compartmentalisation in cAMP signalling: A phase separation perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Central dentinogenic ghost cell tumor of the maxilla: a case report with new imaging findings and review of the literature. [PDF]

open access: yesOral Radiol
Yoshida S   +9 more
europepmc   +1 more source

Catalase activity in the red cell ghost of hypocatalasemia and normal subject. I. Catalase in the red cell ghost of hypocatalasemia and normal subject

open access: yes
An attempt was made to find out the nature of catalase coritained in the red cell, especially in the ghost, For this the red cell ghost isolated were washed several times with CO2-saturated water or deionized water and the catalase activity per gram ...
Nishioka, Keiko
core  

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