Results 161 to 170 of about 240,647 (299)
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Postoperative ileus and gastrointestinal complications following spine surgery: A systematic review of incidence, risk factors, prevention, and treatment. [PDF]
Geraghty E +4 more
europepmc +1 more source
Photo-Acoustic Imaging in GI Surgery
Jimmy Mena, Mahmoud Sallam
openaire +1 more source
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
Endovascular Coil Migration to Duodenal Lumen After Gastroduodenal Artery Embolization in a 90-Year-Old-Woman, Complicating Upper-GI Bleed Management: A Case Report. [PDF]
Hagans TA, Canaff L, Rimer R, Nemec FJ.
europepmc +1 more source
The spatiotemporal dynamics of protein kinase diffusion govern cellular signaling and functions. Although vital for active receptors, the role of pseudokinase dynamics is unclear. Here, we use single‐molecule tracking to link faster diffusion of pseudokinase PTK7 to increased tumor cell invasion and migration.
Yaohua Li +8 more
wiley +1 more source
Life-Threatening Lower GI Bleeding From Sigmoid Colon Metastasis of Cutaneous Angiosarcoma: A Case Report. [PDF]
Roomy A, Pretorius F.
europepmc +1 more source
Hafnium (Hf)‐rich carbon dots (Hf‐rCDs) with high metal content (40.7%) and robust batch production capacity (>2 g per batch) are synthesized via a facile air‐assisted pyrolysis method. In vivo CT imaging demonstrates outstanding performance of Hf‐rCDs across multiple physiological systems and enables high‐resolution visualization of swine cervical ...
Shuo Li +11 more
wiley +1 more source
Emergency staged Whipple procedure for gastroduodenal mucormycosis: a rare life-saving intervention. [PDF]
Raya A +5 more
europepmc +1 more source

