Results 171 to 180 of about 240,647 (299)

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

Impact of surgery and complications on GI recovery after SBO: Insights from the SnapSBO cohort. [PDF]

Colorectal Dis
Lee MJ, Kaplan LJ, Mohseni S, Cimino M, Kurihara H, Martinez-Casas I, Bass GA, SnapSBO Collaborators.   +7 more
europepmc   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Nutritional intake and growth in children with intestinal failure: An exploratory cross-sectional study. [PDF]

Intest Fail
Inamura N, Takeda M, Sasaki M, Nishikawa Y, Tanaka C, Fuda M, Sakurai T, Ando R, Nakamura M, Kudo H, Nagatomi R, Wada M.   +11 more
europepmc   +1 more source

Abstract Journal Upper GI Surgery [PDF]

ANZ Journal of Surgery, 2019
openaire   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Plastic Wound Protector vs Surgical Gauze for Surgical Site Infection Reduction in Open GI Surgery: A Randomized Clinical Trial.

JAMA Surg
Yoo N, Mun JY, Kye BH, Kim CW, Lee JI, Park YY, Kang BM, Park BK, Kwak HD, Kang WK, Bae SU, Oh HK, Hong Y, Kim HJ.   +13 more
europepmc   +1 more source

Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2024 for the Clinical Practice of Inflammatory Bowel Disease-Associated Intestinal Neoplasia (English Version). [PDF]

J Anus Rectum Colon
Ishihara S, Tanaka S, Uraoka T, Saito Y, Takamaru H, Nakase H, Naganuma M, Hisamatsu T, Fujii T, Matsuura M, Matsumoto T, Watanabe K, Ikeuchi H, Uchino M, Okita Y, Okabayashi K, Koganei K, Sugita A, Takahashi K, Hata K, Higashi D, Futami K, Matsuda K, Mizushima T, Watadani Y, Kawachi H, Shimoda M, Sugai T, Yoshida M, Yamaguchi N, Itabashi M, Anzai H, Kishikawa J, Komatsu K, Shinagawa T, Tsushima T, Noguchi T, Okada S, Sugihara K, Ajioka Y.   +39 more
europepmc   +1 more source

A Strain Decoupling Packaging Strategy for High‐Fidelity Ultrathin Silicon Shape Sensors for Soft Medical Robotics

Advanced Science, EarlyView.
Reliable soft sensors are essential for precise control in soft medical robots such as endoscopes. We developed ultrathin silicon piezoresistive sensors and their oil‐lubricated slidable packaging, which enables high‐fidelity shape sensing of silicon gauges by mechanically isolating the sensing element within a dual‐layer film.
Hao Liu, Masahito Takakuwa, Michitaka Yamamoto, Yiwen Wang, Tomoyuki Yokota, Takao Someya, Toshihiro Itoh, Seiichi Takamatsu   +7 more
wiley   +1 more source

Artificial Intelligence in Minimally Invasive and Robotic Gastrointestinal Surgery: Major Applications and Recent Advances. [PDF]

J Pers Med
Pescio M, Marzola F, Distefano G, Leoncini P, Ammirati CA, Barontini F, Dagnino G, Arezzo A.   +7 more
europepmc   +1 more source