Results 221 to 230 of about 4,834,992 (345)

Abstract Journal for Upper GI Surgery [PDF]

ANZ Journal of Surgery, 2015
openaire   +1 more source

Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy

Advanced Science, EarlyView.
ABSTRACT Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assembly.
Yuanqiang Lin, Mingran Dai, Enyong Dai, Rui Kang, Daniel J. Klionsky, Daolin Tang, Yu Sun, Ningning Lv, Junnan Jiang   +8 more
wiley   +1 more source

Perspectives on Education From Gastrointestinal (GI) Cancer Patients in the Deep South: Qualitative Analysis. [PDF]

Cancer Med
Hernandez-Marquez GC, Ivankova NV, English NC, Oslock WM, Abbas A, Harsono AAH, Jones BA, Herbey II, Naik G, Schoenberger-Godwin YM, Chu DI, Pisu M.   +11 more
europepmc   +1 more source

HPB & Upper GI Surgery [PDF]

ANZ Journal of Surgery, 2008
openaire   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Imaging manifestations of Bouveret's syndrome: A rare case report of gallstone-induced ileus. [PDF]

SAGE Open Med Case Rep
Wang T, Ma X, Chai J.
europepmc   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source

Familial Juvenile Polyposis Syndrome: A Case Report of a Cosegregation of SMAD4 Germline Pathogenic Variant c.403C>T and Review of the Literature. [PDF]

Case Rep Surg
Martinez CAR, Pazin GS, Siqueira RM, de Carvalho RB, Camargo MG, Genaro LM, Bonfitto PHL, Ayrizono MLS, Leal RF, Coy CSR.   +9 more
europepmc   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Laparoscopic repair of diaphragmatic hernia with bovine pericardium patch and opportunistic resection of metastatic thymoma. [PDF]

J Surg Case Rep
Jiwane M, Younan E, Sandroussi C, Yan TD, Laurence JM.   +4 more
europepmc   +1 more source