Results 251 to 260 of about 2,917,145 (365)

Post-ESOphagectomy patients presenting for General Anesthesia INduction: A systematic review of the literature (PESO-GAIN-R). [PDF]

open access: yesSaudi J Anaesth
Tabrizi NS   +6 more
europepmc   +1 more source

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim   +7 more
wiley   +1 more source

CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou   +15 more
wiley   +1 more source

Modified low-cost EndoVac is safe and efficacious for treatment of postoperative leaks even at low pressures. [PDF]

open access: yesSurg Endosc
Sundaram S   +8 more
europepmc   +1 more source

Carbon‐Coated Probiotics Restore Intestinal Homeostasis to Promote Damage Repair in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
Carbon‐coated Lactobacillus rhamnosus GG (C dots@LGG) enhances the antioxidant effects of LGG and safeguards the probiotics to target the inflamed colon. This reduces inflammation and oxidative damage, repairs the intestinal barrier, regulates the microbiota, and alleviates colitis.
Xue Chen   +9 more
wiley   +1 more source

Examining spatial microbiome variations across gastrointestinal tract regions in obesity. [PDF]

open access: yesSci Rep
Rehner J   +10 more
europepmc   +1 more source

Lutetium‐Based Nanoprobes for Radiosensitization with Immune Microenvironment Remodeling and NIR‐II Fluorescence Imaging‐Guided Surgery in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Enhancing radiosensitization, modulating the tumor immune microenvironment, and ensuring complete resection are crucial for colorectal cancer (CRC) treatment. This study presents a multifunctional NIR‐II fluorescent nanoprobe, RVLu@ICG, which enhances radiosensitization, remodels the tumor immune microenvironment, and enables precise image‐guided ...
Yongying Dang   +10 more
wiley   +1 more source

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