Results 71 to 80 of about 2,917,145 (365)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Predicting post‐discharge cancer surgery complications via telemonitoring of patient‐reported outcomes and patient‐generated health data

Journal of Surgical Oncology, 2021
Post‐discharge oncologic surgical complications are costly for patients, families, and healthcare systems. The capacity to predict complications and early intervention can improve postoperative outcomes.
Lorenzo A. Rossi, L. Melstrom, Y. Fong, V. Sun   +3 more
semanticscholar   +1 more source

Risk-Assessment of Esophageal Surgery: Diagnosis and Treatment of Celiac Trunk Stenosis

The Thoracic & Cardiovascular Surgeon Reports, 2018
Anastomotic leakage of the gastric conduit following surgical treatment of esophageal cancer is a life-threatening complication. An important risk factor associated with anastomotic leakage is calcification of the supplying arteries of the gastric ...
Rosa G.M. Lammerts, Marc J. van Det, Rob H. Geelkerken, Ewout A. Kouwenhoven   +3 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Survival outcomes fifteen years after minimally invasive esophagectomy

Discover Oncology
Background and objectives Minimally invasive esophagectomy (MIO) offers a less traumatic resection for cancer patients resulting in improved quality of life.
Amira Orabi, Gauri Chillarge, Davide Di Mauro, Dharmarajah Veeramootoo, Ikechukwu Njere, Antonio Manzelli, Shahjehan Wajed   +6 more
doaj   +1 more source

Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett, Karl Everett, Colleen J. Maxwell, Feng Zhu, Ayesha Asaf, Ping Li, Kyla A. McKay, Yinshan Zhao, Ruth Ann Marrie   +8 more
wiley   +1 more source

Indications and Outcomes of Hepatopancreatoduodenectomy for Gallbladder Carcinoma and Extrahepatic Cholangiocarcinoma: A Single Center Retrospective Study

JGH Open
Introduction Hepatopancreatoduodenectomy (HPD) is the only definitive approach to achieve curative resection in locally advanced biliary tract cancers.
S. D. Adhikari, R. Pahari, P. Maharjan, Y. Limbu, S. Regmee, R. Ghimire, D. K. Maharjan, S. K. Shrestha, P. B. Thapa   +8 more
doaj   +1 more source

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Can Dehn surgery yield three connected summands?

, 2009
A consequence of the Cabling Conjecture of Gonzalez-Acu\~{n}a and Short is that Dehn surgery on a knot in $S^3$ cannot produce a manifold with more than two connected summands.
Howie, James
core   +2 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source