Results 111 to 120 of about 5,839,150 (260)

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Case report: Giant cell tumor of bone in the mandible of a goat—diagnostics, surgical treatment, and outcome

open access: yesFrontiers in Veterinary Science
Neoplastic processes of the mandible and their treatment are rarely reported in large animal species. Specifically, giant cell tumor of bone is an uncommon tumor in animals and has been associated in humans with locally invasive behavior and a high ...
Nora M. Biermann   +5 more
doaj   +1 more source

Giant-Cell Tumor of the Distal Ulna Treated by Wide Resection and Ulnar Support Reconstruction: A Case Report

open access: yesCase Reports in Medicine, 2010
Giant-cell tumor of bone occurred in the distal end of the ulna is extremely uncommon. A 23-year-old male had a giant-cell tumor occurred in the distal end of the ulna.
Akio Minami   +5 more
doaj   +1 more source

Deciphering transcriptome complexity via long‐read sequencing

open access: yesiMeta, EarlyView.
Long‐read sequencing is transforming transcriptomics from gene‐level quantification to isoform‐resolved interpretation by directly resolving full‐length transcript structures, transcription in repetitive regions, and linked molecular features. This review provides an end‐to‐end roadmap covering sequencing platforms, library preparation strategies ...
Chuwen Xu   +21 more
wiley   +1 more source

Old disease, new twist

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari   +4 more
wiley   +1 more source

Molecular biology of giant viruses' DNA replication machinery [PDF]

open access: yes, 2013
Viruses are the most widespread and abundant entity on this planet, further constituting the largest part of the genosphere. The majority of these infectious agents are miniature, having been described as being smaller than the smallest bacteria.
Evripioti, Antonia Alexandra
core   +1 more source

Giant Cell Tumor of the Rib

open access: yes, 2006
Giant cell tumors of the bone are approximately 5% of all bone neoplasms. They place around the epiphysis of long bones in 75-90% of patients following after skeletal maturity. Only 0.5-0.6% of the giant cell tumor are located in the rib.
EROĞLU, AHMET   +3 more
core  

Patient-specific Distal Tibia Prosthesis for Reconstruction in a Case of Recurrent Giant Cell Tumor – A Case Report

open access: yes
Introduction: The advent of 3D-printed, patient-specific implants has revolutionized limb salvage surgeries, offering precise, personalized solutions for complex skeletal reconstructions.
Basra, Mohit   +7 more
core   +1 more source

Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]

open access: yes, 2013
Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
core  

Intraoperative Evaluation of Sarcoma Surgical Margins With Indocyanine Green Fluorescence Imaging: Results From an Observational Study

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Sarcomas are rare malignancies that affect both adults and children. Surgical removal with negative histopathological margins is the foundation of sarcoma treatment. Failure to achieve negative margins puts patients at risk of local recurrence (LR). LR rates range between 10% and 30%.
Sumail Bhogal   +13 more
wiley   +1 more source

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