Results 131 to 140 of about 61,604 (250)

Rankl expression as a prognostic marker in stage III giant cell tumour of the bone [PDF]

open access: yes, 2015
Introduction: Giant cell tumour of bone is an aggressive benign bone tumor composed of unstable spindle shaped neoplastic mononuclear stromal cells and reactive components osteoclast like giant cells. GCT in Asian population including Malaysia, presented
Abdul Ghani , Nur Sabrina
core  

When an Oral Lesion Uncovers Hyperparathyroidism: A Peripheral Brown Tumor Case

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Oral lesions may represent the first sign of an underlying systemic disease. Giant cell lesions in the oral cavity should prompt investigation for hyperparathyroidism, as early recognition of brown tumors allows appropriate systemic management and may lead to lesion regression after treatment of the endocrine disorder.
Bruno Teixeira Gonçalves Rodrigues   +6 more
wiley   +1 more source

Hydatid Cyst of the Thyroid Gland With Concurrent Hepatic Involvement: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Hydatidosis, caused by Echinococcus granulosus, most commonly affects the liver and lungs, while thyroid involvement is exceptionally rare and can mimic other cystic thyroid lesions. We report a 40‐year‐old woman with no history of animal exposure who presented with anterior neck swelling, odynophagia, and abdominal discomfort. She had a prior
Hana Saffar, Aysan Nozheh, Maral Edalati
wiley   +1 more source

Surgical Resection of Lumbar Spine Osteoblastoma With Secondary Aneurysmal Bone Cysts Through a Combined Transpsoas and Posterior Approach: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Aggressive lumbar osteoblastoma with secondary aneurysmal bone cysts is rare and may involve both posterior elements and vertebral bodies. When extensive multilevel involvement is present, a combined posterior and transpsoas approach can facilitate complete tumor resection, restore spinal stability, and achieve favorable neurological and ...
Enliang Chen   +8 more
wiley   +1 more source

Decoding the Hexosamine Biosynthesis Pathway: Implications for Novel Therapeutic Strategies in Sarcoma

open access: yesJournal of Cellular Physiology, Volume 241, Issue 5, May 2026.
ABSTRACT Cancer cells rewire their metabolism to sustain a high proliferation rate. Sensing external cues is essential to match the metabolic fluxes of the cells to the external stimuli. As part of the glucose metabolism, the hexosamine biosynthesis pathway (HBP) is considered a nutrient‐sensing pathway. The HBP produces UDP‐GlcNAc, a key precursor for
Pegah Rahimizadeh   +4 more
wiley   +1 more source

Cell Mechanics in Cancer: Integrating Mechanotransduction Pathways Within the Tumor Microenvironment

open access: yesJournal of Cellular Physiology, Volume 241, Issue 5, May 2026.
ABSTRACT Single‐cell mechanical properties such as stiffness, elasticity, and viscosity, are crucial in governing biological processes like migration, proliferation, and differentiation. In cancer, the mechanical properties of cells undergo significant alterations, which contribute to tumor growth, metastasis, and resistance to therapy.
Merve Sevgi   +7 more
wiley   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao   +7 more
wiley   +1 more source

Case Report: Giant cell lesions in the Maxillofacial region: diagnostic points and treatment strategies

open access: yesFrontiers in Oncology
ObjectiveGiant cell-rich lesions in the maxillofacial region are relatively rare, and comprehensive clinical differential diagnostic protocols are currently lacking.
Xiaohan Gao   +12 more
doaj   +1 more source

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