Results 11 to 20 of about 61,604 (250)

Effect of bisphosphonates on bone giant cell tumor recurrence: a meta-analysis

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2022
Background We examined the impact of bisphosphonates as adjuvant therapy on the recurrence of giant cell bone tumors and the impact of various tumor stages and surgical techniques on this effect.
Marwa Mohsen   +4 more
doaj   +1 more source

Current therapies and future prospective for locally aggressive mesenchymal tumors

open access: yesFrontiers in Oncology, 2023
Locally aggressive mesenchymal tumors comprise a heterogeneous group of soft tissue and bone tumors with intermediate histology, incompletely understood biology, and highly variable natural history.
Alessandra Maleddu   +3 more
doaj   +1 more source

Accuration of Fine Needle Aspiration Biopsy in Musculoskeletal Tumour [PDF]

open access: yes, 2016
Fine needle aspiration biopsy (FNAB) has been reported to be the preferable choice of biopsy for musculoskeletal tumour. While FNAB appears to have advantages to core biopsy in the aspect of simplicity and cost, the diagnostic accuracy should be the most
Dewo, P. (Punto)   +3 more
core   +4 more sources

Role of cancer stem cells in the development of giant cell tumor of bone

open access: yesCancer Cell International, 2020
The primary bone tumor is usually observed in adolescence age group which has been shown to be part of nearly 20% of the sarcomas known today. Giant cell tumor of bone (GCTB) can be benign as well as malignant tumor which exhibits localized dynamism and ...
Abdul Rouf War   +7 more
doaj   +1 more source

Giant Cell-Rich Tumors of Bone [PDF]

open access: yesSurgical Pathology Clinics, 2021
The term giant cell-rich tumors of bone refers to a shared morphologic pattern in a group of different osseous lesions, that is, the abundance of osteoclastlike giant cells. Fitting with a broad spectrum of clinical presentations and biological behavior, the recent detection of characteristic molecular alterations in giant cell tumor of bone (H3-3 ...
Wolfgang, Hartmann   +2 more
openaire   +2 more sources

DISTAL TIBIAL RECONSTRUCTION WITH INTRAMEDULLARY NAIL COMBINED WITH T-PLATE FOLLOWING EN-BLOC-EXCISION OF GIANT CELL TUMOR OF DISTAL TIBIA: CASE-REPORT

open access: yesJournal Orthopaedi and Traumatology Surabaya, 2021
Background: Giant cell tumor is locally aggressive benign tumor that occur more common in distal femur, proximal tibia, and distal radius, and has tendency for recurrence and has capability for metastatize.
Mujaddid Idulhaq   +2 more
doaj   +1 more source

Giant-cell Tumor of the Patella [PDF]

open access: yes, 2012
We report a 38-year old man with a giant-cell tumor in a rare site, the patella. Primary patellar neoplasms are highly unusual. According to a survey by the Bone and Soft Tissue Tumor Committee of the Japanese Orthopaedic Association, of more than 2,126 ...
Kojima, Toshio   +4 more
core   +1 more source

Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases. [PDF]

open access: yes, 2019
Denosumab has been used successfully to treat disease-associated osteoclast overactivity, including giant cell tumor of bone. Given its mechanism of action, denosumab is a potent potential treatment of other osteoclast bone dysplasias including central ...
Bernthal, Nicholas M   +8 more
core   +2 more sources

Multicentric Giant Cell Tumor of Bone

open access: yesOrthopedics, 2023
The typical presentation of giant cell tumor of bone is a solitary lesion involving the meta-epiphyseal region of the long bones. The presence of more than one distinct giant cell tumor in the same patient is rare. This study reports on 7 patients with multicentric giant cell tumor of bone. Clinical and radiologic features were reviewed to
Errani, Costantino   +6 more
openaire   +4 more sources

Primary hyperparathyroidism diagnosed after surgical ablation of a costal mass mistaken for giant-cell bone tumor: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Primary hyperparathyroidism is a common endocrine disorder characterized by elevated parathyroid hormone levels, which cause continuous osteoclastic bone resorption.
Vera Lara   +6 more
doaj   +1 more source

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