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GIANT CELL TUMOR OF BONE: A MULTICENTER EPIDEMIOLOGICAL STUDY IN BRAZIL. [PDF]
Acta Ortop BrasBecker RG +5 more
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Excision of a Giant Cell Tumor With Bone Grafting and Bone Cementing of the Proximal Humerus: A Case Report. [PDF]
CureusGharpinde MR +4 more
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H3.3-G34W in giant cell tumor of bone functionally aligns with the exon choice repressor hnRNPA1L2. [PDF]
Cancer Gene TherLee E, Park YJ, Lindroth AM.
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Current Oncology Reports, 2002
Giant cell tumor of bone is an enigmatic osseous neoplasm that is histologically benign but clinically shows local aggression and metastatic potential. The absence of clinical, radiographic, or pathologic features that are predictive of tumor behavior and patient outcome has resulted in recent attention to the pathobiology of giant cell tumor of bone ...
exaly +3 more sources
Giant cell tumor of bone is an enigmatic osseous neoplasm that is histologically benign but clinically shows local aggression and metastatic potential. The absence of clinical, radiographic, or pathologic features that are predictive of tumor behavior and patient outcome has resulted in recent attention to the pathobiology of giant cell tumor of bone ...
exaly +3 more sources
Giant Cell Tumor of Bone: An Update
Current Oncology Reports, 2021To highlight the new developments in the management of advanced giant cell tumor of bone, a rare locally aggressive benign tumor, which was traditionally managed with surgery alone by either curettage and local adjuvant therapy, wide resection, or marginal excision. Here, we review the current role of systemic therapy for management of locally advanced
Atrayee Basu Mallick
exaly +3 more sources
Orthopedic Clinics of North America, 2006
Giant cell tumor is a common benign bone tumor that possesses specific features including location at the end of long bone, a strong tendency toward local recurrence, and the rare capacity to metastasize to the lungs. Preferred treatment usually consists of extensive curettage and filling of the cavity with bone graft or cement.
William M, Mendenhall +4 more
openaire +4 more sources
Giant cell tumor is a common benign bone tumor that possesses specific features including location at the end of long bone, a strong tendency toward local recurrence, and the rare capacity to metastasize to the lungs. Preferred treatment usually consists of extensive curettage and filling of the cavity with bone graft or cement.
William M, Mendenhall +4 more
openaire +4 more sources
Radiology, 1958
THE PRESENCE of multinucleated giant cells in a variety of bone lesions has led to inclusion of certain neoplastic, inflammatory, developmental, and metabolic disorders of bone under the diagnosis of giant-cell tumor or giant-cell tumor variant. In 1940, Jaffe, Lichtenstein, and Portis (1) offered a specific definition of giant-cell tumor which has ...
V R, GEE, D G, PUGH
openaire +4 more sources
THE PRESENCE of multinucleated giant cells in a variety of bone lesions has led to inclusion of certain neoplastic, inflammatory, developmental, and metabolic disorders of bone under the diagnosis of giant-cell tumor or giant-cell tumor variant. In 1940, Jaffe, Lichtenstein, and Portis (1) offered a specific definition of giant-cell tumor which has ...
V R, GEE, D G, PUGH
openaire +4 more sources
Radiologic Clinics of North America, 1993
Giant cell tumor is a lesion that usually presents with a radiographically characteristic appearance in a predictable location and patient population. It has a few rare presentations such as pulmonary metastases and multifocal lesions. Prognosis of ultimate tumor behavior is dependent on surgical staging (which requires careful radiographic analysis to
B J, Manaster, A J, Doyle
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Giant cell tumor is a lesion that usually presents with a radiographically characteristic appearance in a predictable location and patient population. It has a few rare presentations such as pulmonary metastases and multifocal lesions. Prognosis of ultimate tumor behavior is dependent on surgical staging (which requires careful radiographic analysis to
B J, Manaster, A J, Doyle
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Journal of the American Academy of Orthopaedic Surgeons, 2013
Giant cell tumor (GCT) of bone is one type of giant cell-rich lesion of bone. This benign mesenchymal tumor has characteristic multinuclear giant cells. Mononuclear stromal cells are the physiologically active and diagnostic cell type. Most GCTs are located in the epiphyseal regions of long bones.
Kevin A, Raskin +4 more
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Giant cell tumor (GCT) of bone is one type of giant cell-rich lesion of bone. This benign mesenchymal tumor has characteristic multinuclear giant cells. Mononuclear stromal cells are the physiologically active and diagnostic cell type. Most GCTs are located in the epiphyseal regions of long bones.
Kevin A, Raskin +4 more
openaire +2 more sources
New England Journal of Medicine, 1956
IN 1920 Dr. E. A. Codman, of Boston, organized the Registry of Bone Sarcoma. A committee consisting of Dr. Codman, Dr. Ewing and Dr. Bloodgood studied a large number of cases of bone tumors, and from them they separated a group of benign giant-cell tumors.
E M, DALAND, C R, HAINES
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IN 1920 Dr. E. A. Codman, of Boston, organized the Registry of Bone Sarcoma. A committee consisting of Dr. Codman, Dr. Ewing and Dr. Bloodgood studied a large number of cases of bone tumors, and from them they separated a group of benign giant-cell tumors.
E M, DALAND, C R, HAINES
openaire +2 more sources