Results 41 to 50 of about 72,548 (342)
Emerging roles of telomeric chromatin alterations in cancer [PDF]
, 2019 Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres need the establishment of a protective chromatin structure based on the interplay between the ...
Biroccio, Annamaria +2 more
core +1 more source
Serglycin induces osteoclastogenesis and promotes tumor growth in giant cell tumor of bone
Cell Death and Disease, 2021 Giant cell tumor of bone (GCTB) is an aggressive osteolytic bone tumor characterized by the within-tumor presence of osteoclast-like multinucleated giant cells (MGCs), which are induced by the neoplastic stromal cells and lead to extensive bone ...
Yunfei He +19 more
semanticscholar +1 more source
Journal of Bone Oncology, 2019 Background: Although denosumab has been approved as an antiresorptive agent for giant cell tumor of bone, its efficacy has not been proven. Objectives: To compare the efficacy and safety of denosumab and zoledronic acid treatment in patients with ...
Shenglong Li, Peng Chen, Qiankun Yang
doaj +1 more source
A chondroblastic osteosarcoma of the coronoid process mimicking a fragmented coronoid process in a dog [PDF]
, 2016 A 6-year-old Rhodesian Ridgeback was presented with a 1.5 year history of right forelimb lameness. Clinical, radiological and computed tomographic findings suggested the presence of fragmented medial coronoid process.
Cirkel, Koen +4 more
core +1 more source
Folia Medica, 2018 Giant cell tumor of bone is a histologically benign but locally aggressive osteolytic lesion, capable of spreading ‘benign’ metastases mainly to the lungs. Since its description as a separate entity, surgery has been the mainstay of treatment.
Marinova Violeta V. +4 more
doaj +1 more source
Giant Cell Tumor of Bone in Patients under 16 Years Old: A Single-Institution Case Series
Cancers, 2021 Simple Summary Giant cell tumor of the bone is a locally aggressive, rarely metastasizing tumor that accounts for about 5% of bone tumors; it generally occurs in patients between 20 and 45 years old.
F. Ambrosi +8 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Radiotherapy damages bone and disrupts osteocyte function, yet mechanically mediated protection remains largely unexplored. This study demonstrates that low‐magnitude, high‐frequency (LMHF) vibration mitigates irradiated osteocyte apoptosis, restores their ability to regulate breast cancer extravasation, and acts synergistically with radiotherapy to ...
Xin Song +7 more
wiley +1 more source
Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Journal of the Bulgarian Orthopaedics and Trauma Association, 2023 Giant cell tumor of bone is a histologically benign bone neoplasia that clinically has an aggressive course. In rare cases, it can give "benign" lung metastases or undergo malignant transformation.
Luben Stokov +4 more
doaj +3 more sources
Tumor de Células Gigantes del Primer Metacarpiano [PDF]
, 1991 Se presenta un caso de tumor de células gigantes que afecta al primer metacarpiano. El tratamiento consistió en la resección en bloque del metacarpiano y su sustitución por injerto cortico-esponjoso de cresta ilíaca.A case of giant cell tumor affecting ...
Arríete Peris, J. C. +3 more
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