Results 81 to 90 of about 72,548 (342)

Histological Regression of Giant Cell Tumor of Bone Following RANK Ligand Inhibition

Journal of Investigative Medicine High Impact Case Reports, 2014
Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ...
Martin F. Dietrich MD, PhD, Dominick Cavuoti MD, Michael Landay MD, Yull E. Arriaga MD   +3 more
doaj   +1 more source

Imaging of giant cell tumor of bone

Indian Journal of Orthopaedics, 2007
Giant cell tumor (GCT) of bone is a benign but locally aggressive and destructive lesion generally occurring in skeletally mature individuals. Typically involving the epiphysiometaphyseal region of long bones, the most common sites include the distal femur, proximal tibia and distal radius.
Purohit, Shaligram, Pardiwala, Dinshaw N
openaire   +3 more sources

Late‐Onset Spondyloarthritis Presenting as Glucocorticoid‐Resistant Polymyalgia Rheumatica: A Hitherto Underappreciated Entity in Which Tumor Necrosis Factor or Interleukin ‐17 Blockade May Have a Therapeutic Role

Arthritis &Rheumatology, EarlyView.
Objective Polymyalgia rheumatica (PMR) is an age‐related inflammatory disease with shoulder/hip girdle involvement. Magnetic resonance imaging (MRI) reveals extracapsular/entheseal soft tissue involvement in both PMR and spondyloarthritis (SpA), with sacroiliac joint and perientheseal spinal bone marrow edema (BME) being characteristic of SpA ...
Kerem Abacar, Gabriele De Marco, Jake Weddell, Katya Meridor, Tom Macleod, Andrew Scarsbrook, Kulveer Mankia, Edward Vital, Andrew Barr, Colin Pease, Helena Marzo‐Ortega, Sarah L. Mackie, Dennis McGonagle   +12 more
wiley   +1 more source

Denosumab May Increase the Risk of Local Recurrence in Patients with Giant-Cell Tumor of Bone Treated with Curettage

Journal of Bone and Joint Surgery. American volume, 2018
Background: Recent clinical studies have suggested that denosumab is associated with tumor response and reduced surgical morbidity in patients with giant-cell tumor of bone (GCTB).
C. Errani, S. Tsukamoto, G. Leone, A. Righi, M. Akahane, Yasuhito Tanaka, D. Donati   +6 more
semanticscholar   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Giant-Cell Tumor of the Distal Ulna Treated by Wide Resection and Ulnar Support Reconstruction: A Case Report

Case Reports in Medicine, 2010
Giant-cell tumor of bone occurred in the distal end of the ulna is extremely uncommon. A 23-year-old male had a giant-cell tumor occurred in the distal end of the ulna.
Akio Minami, Norimasa Iwasaki, Kinya Nishida, Makoto Motomiya, Katsuhisa Yamada, Daisuke Momma   +5 more
doaj   +1 more source

Do we need internal fixation devices for giant cell tumors around knee joint? An outcome study

Journal of Orthopaedic Diseases and Traumatology, 2018
Introduction: Giant cell tumors around the knee joint are the most common aggressive benign tumors. Several limb sparing and limb ablation surgeries are practiced with varying level of success.
Ritesh Runu, Vidya Sagar, Ashutosh Kumar, Arnab Sinha, Santosh Kumar   +4 more
doaj   +1 more source

Pleomorphic sarcoma [PDF]

, 2013
67-year-old female who was referred from her general practitioner because of uncontrolled right popliteal knee pain which was very severe and continuously deteriorating. She could not bend her knee and sleep because of the pain.
Bertuello, Isaac, Bonnici, Maria
core  

Systematic review and meta-analysis of en bloc vertebrectomy compared with intralesional resection for giant cell tumors of the mobile spine [PDF]

, 2016
Study Design Systematic review and meta-analysis. Objective To compare the recurrence and perioperative complication rate of en bloc vertebrectomy (EV) and intralesional resection (IR) in the giant cell tumor of the mobile spine (SGCT).
Buchowski, Jacob M, Bumpass, David B, Luksanapruksa, Panya, Singhatanadgige, Weerasak   +3 more
core   +2 more sources

Challenges of denosumab in giant cell tumor of bone, and other giant cell-rich tumors of bone

Current Opinion in Oncology, 2019
Purpose of review Giant cell tumor of bone (GCTB) is an uncommon benign primary bone tumor, consisting of receptor activator of nuclear factor kappa-B (RANK) expressing reactive osteoclast-like giant cells and neoplastic spindle-shaped cells.
A. Lipplaa, S. Dijkstra, H. Gelderblom
semanticscholar   +1 more source