A double‐positive surface marker detection approach was developed to conduct exosome surface protein detection in serum samples. It reaches single‐exosome detection, and over 300 exosome protein parameters are analyzed. The diagnostic accuracy achieved 90% in differentiation of high‐grade serous/serous ovarian carcinoma patients, benign patients, and ...
Jiaoyan Qiu+7 more
wiley +1 more source
Giant Solitary Nodular Trichoepithelioma: A Case Report and Review of Literature
A giant solitary nodular trichoepithelioma (GST) is a rare trichogenic tumor, which may present as a pigmented lesion. A 45-year-old female was diagnosed as having a giant solitary nodular trichoepithelioma on her right forearm.
Sunder Goyal+3 more
doaj +1 more source
Giant Basal Cell Carcinoma of the Back: A Case Report and Review of the Literature [PDF]
Basal cell carcinoma (BCC) is the most common cutaneous malignancy and the most common human malignancy in general. Out of all basal cell carcinomas, giant basal cell carcinoma represents less than 1%. Only 10% of all basal cell carcinomas are located on
Branko Bogdanić+5 more
core +1 more source
Basal cell skin cancer with metastasis to subcutaneous fat—a case report
Basal cell carcinoma (BCC) is a malignant neoplasm of the skin that originates from the cells of the basal layer of the epidermis and is the most common skin cancer worldwide, accounting for more than 75% of all nonmelanoma skin cancers.
Veronika Rumyantseva+5 more
doaj +1 more source
Mielolipoma adrenal gigante associado à deficiência da 21-hidroxilase: associação não usual simulando um carcinoma adrenocortical secretor de androgênios [PDF]
The objective of this study was to describe a case of giant myelolipoma associated with undiagnosed congenital adrenal hyperplasia (CAH) due to 21-hydroxylase (21OH) deficiency.
CASTRO, Margaret de+6 more
core +2 more sources
SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai+6 more
wiley +1 more source
Giant Cornu Cutaneum Superimposed on Basal Cell Carcinoma [PDF]
Cornu cutaneum (CC) is a clinical term that describes the horn-like keratotic lesions extending vertically from the skin. Benign, premalignant or malignant lesions may be present at the base of CC. Seborrhoeic keratosis and squamous cell carcinoma (SCC) are the most commonly reported benign and malignant forms, respectively.
A Dikmen+5 more
openaire +3 more sources
Mitochondrial dysfunction: Related diseases, influencing factors, and detection
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li+9 more
wiley +1 more source
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li+5 more
wiley +1 more source
Giant Basal Cell Carcinoma of the Forehead: A Case Report [PDF]
Giant basal cell carcinoma (GBCC) is defined as a tumor 5cm or greater in diameter. They present less than 1% of all basal cell carcinomas. We present a case of an 85-year-old male patient with a giant ulcerating tumor of the left forehead (measuring ...
Marijan Kovačić+3 more
core +1 more source