Results 121 to 130 of about 21,023 (227)

A Granulomatous Puzzle: Tubercular Lymphadenitis Without AFB Clues

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Tubercular lymphadenitis (TBL) is the most common form of extrapulmonary tuberculosis (EPTB), accounting for 20%–40% of EPTB cases. We present you a case of a 45‐year‐old male presented with gradually progressive swelling in the lower right side of the jaw for 2 months. At his initial consultation at another center, a diagnosis of carcinoma of
Anupriya Sah   +3 more
wiley   +1 more source

Molecular Mechanisms and Therapeutic Potential of DJ‐1 in Skeletal Muscle Homeostasis and Disease

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
DJ‐1 protein functions as a redox‐sensing guardian in skeletal muscle by coordinating antioxidant defense, mitochondrial homeostasis, metabolic adaptation, and anti‐atrophy signaling. Enhancing its function holds promise as a potential therapeutic strategy for muscle atrophy, ALS, and metabolic myopathies.
Yue Zhang   +5 more
wiley   +1 more source

Beyond bacterial defences: the role of lysozyme in cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang   +4 more
wiley   +1 more source

Clinical, Pathological, and Imaging Study of Pilomatrixoma: A Retrospective Study

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims A retrospective analysis was conducted on the clinical, pathological, and imaging features of 471 cases of pilomatrixoma, aiming to enhance clinicians' understanding of pilomatrixoma. Methods A total of 471 cases of pilomatrixoma diagnosed and surgically treated in the Affiliated Hospital of Southwest Medical University ...
Qi Hao   +4 more
wiley   +1 more source

Single‐Port Transoral Robotic Surgery for Head and Neck Lesions and Obstructive Sleep Apnea: A Prospective Real‐World Case Series From Taiwan

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 1, February 2026.
Setup of the da Vinci SP system. (A) The SP port is positioned transorally with the robotic cart docked at the patient’s head. (B) Two or three instruments and a 3D endoscope are inserted via a single port. ABSTRACT Objectives To assess the clinical practicality, procedural characteristics, and short‐term recovery outcomes of single‐port transoral ...
Ting‐Shen Lin   +5 more
wiley   +1 more source

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu   +4 more
wiley   +1 more source

Condyloma-like squamous cell carcinoma of the vulva: report of two midline cases [PDF]

open access: yes, 2012
Shyam B Verma,1 Uwe Wollina21Nirvana Clinic, Vadodara, Gujarat, India; 2Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, GermanyAbstract: Vulvar cancer is uncommon and may be confused with genital ...
Verma SB, Wollina U
core   +1 more source

CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS [PDF]

open access: yes, 2018
Background. Currently, there are no genetic testing guidelines for patients with a primary brain tumor (PBT). This population is largely understudied in terms of the family history, tumor grade, pathology, and their relation to genetic contribution.
Azam, Sarah
core   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

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