Root-knot nematode feeding site development is impaired by cyclin-dependent kinase inhibitors [PDF]
Plant-parasitic nematodes of the genera Meloidogyne trigger the formation of giant cells that undergo recurring acytokinetic mitosis and endocycles. Expression analyses of key cell cycle genes showed their early induction in the nematode feeding site ...
Abad, Pierre +5 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Chromosomal and histological evidences of infertility in F2 and F2 backcross. Hybrid generations of Clarias anguillaris and Heterobranchus longifilis [PDF]
Male meiosis was studied in 9 different mating combinations in parental, first, second and backcross generation hybrids of Clarias anguillaris and Heterobranchus longifilis. 27 bivalents were recorded in metaphase I for seven mating combinations.
Aluko, P.O.
core
Dynamics and Selection of Giant Spirals in Rayleigh-Benard Convection
For Rayleigh-Benard convection of a fluid with Prandtl number \sigma \approx 1, we report experimental and theoretical results on a pattern selection mechanism for cell-filling, giant, rotating spirals.
A. Belmonte +26 more
core +1 more source
The organisation of spinoparabrachial neurons in the mouse [PDF]
The anterolateral tract (ALT), which originates from neurons in lamina I and the deep dorsal horn, represents a major ascending output through which nociceptive information is transmitted to brain areas involved in pain perception.
Cameron, Darren +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
What is the significance of bone marrow examination in presence of peripheral cytopenias? It is still regarded as a mandatory investigation to diagnose hematological disorders.
Farrukh Zia, Natasha Ali
doaj +1 more source
Giant Cell Granulomas of Jaws: a Clinicopathologic Study
Objectives: The purpose of present study was to investigate and correlate the histological findings in central giant cell granuloma and peripheral giant cell granuloma of jaws with clinical and radiographic interpretations of the lesion.
Shruti Gupta +4 more
doaj +1 more source
Epulis gigantocelularis: imunohistochemická analýza MGMT, p53, OPN a MMP-1 [PDF]
Object: The object of this study was to analyze the expression of MGMT, p53, OPN and ММР-1 in giant-cell epulis. Methods: 10 giant-cell epulis were evaluated for expression of MGMT, p53, OPN and ММР-1 by immunohistochemistry. Results: Strong giant-cell
Kuzenko, Yevhen Viktorovych +5 more
core

