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Headache: The Journal of Head and Face Pain, 2014 Giant cell arteritis ( GCA ) is a medium and large‐vessel vasculitis, which is an important cause of secondary headache in older adults. While GCA has a classic presentation occurring after the age of 50, atypical presentations (eg, fever of unknown ...
Jonathan H, Smith, Jerry W, Swanson
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Journal of Neuro-Ophthalmology, 2016
Giant cell arteritis (GCA) is an immune-mediated large-vessel vasculitis with a complex etiology in which a cross talk between environmental and genetic factors may affect its susceptibility and phenotypic expression. During the last decades, a large number of candidate gene studies explored the genetic component of GCA.
Jem, Ninan +2 more
+7 more sources
Giant cell arteritis (GCA) is an immune-mediated large-vessel vasculitis with a complex etiology in which a cross talk between environmental and genetic factors may affect its susceptibility and phenotypic expression. During the last decades, a large number of candidate gene studies explored the genetic component of GCA.
Jem, Ninan +2 more
+7 more sources
Current Pain and Headache Reports, 2006
Giant cell, or temporal, arteritis is a vasculitis of the medium and large arteries that preferentially involves vessels originating from the arch of the aorta. Classically, this disease manifests in an older individual with new-onset persistent headache, an abnormal temporal artery on examination, and increased serum inflammatory markers. The level of
Todd J, Schwedt +2 more
+7 more sources
Giant cell, or temporal, arteritis is a vasculitis of the medium and large arteries that preferentially involves vessels originating from the arch of the aorta. Classically, this disease manifests in an older individual with new-onset persistent headache, an abnormal temporal artery on examination, and increased serum inflammatory markers. The level of
Todd J, Schwedt +2 more
+7 more sources
Current Opinion in Ophthalmology, 2008
Giant-cell arteritis frequently poses diagnostic and therapeutic challenges. This article summarizes recent investigations concerning diagnosis and treatment of giant-cell arteritis.Efforts to improve diagnostic accuracy have centered on serologic markers and imaging techniques.
Xiang, Wang +7 more
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Giant-cell arteritis frequently poses diagnostic and therapeutic challenges. This article summarizes recent investigations concerning diagnosis and treatment of giant-cell arteritis.Efforts to improve diagnostic accuracy have centered on serologic markers and imaging techniques.
Xiang, Wang +7 more
+7 more sources
Current Opinion in Ophthalmology, 2007
Giant cell arteritis is an important cause of blindness in patients over 60 years of age. We attempt to identify the important clinical aspects in the diagnosis and management of this disorder, so that treatment may be instituted expeditiously to limit visual loss.In addition, we identify current areas of standards in the investigation and treatment of
Helen V, Danesh-Meyer, Peter J, Savino
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Giant cell arteritis is an important cause of blindness in patients over 60 years of age. We attempt to identify the important clinical aspects in the diagnosis and management of this disorder, so that treatment may be instituted expeditiously to limit visual loss.In addition, we identify current areas of standards in the investigation and treatment of
Helen V, Danesh-Meyer, Peter J, Savino
+6 more sources
Current Treatment Options in Neurology, 2004
Patients with a suspected diagnosis of giant cell arteritis (GCA) should be started on high-dose corticosteroid therapy without delay. A temporal artery biopsy should be performed after initiation of therapy to confirm the diagnosis. Patients with acute visual or neurologic symptoms present a neuro-ophthalmic emergency.
Jennifer K., Hall, Laura J., Balcer
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Patients with a suspected diagnosis of giant cell arteritis (GCA) should be started on high-dose corticosteroid therapy without delay. A temporal artery biopsy should be performed after initiation of therapy to confirm the diagnosis. Patients with acute visual or neurologic symptoms present a neuro-ophthalmic emergency.
Jennifer K., Hall, Laura J., Balcer
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Rheumatic Disease Clinics of North America, 1995
Whereas giant cell arteritis (GCA) was considered a rare disease 50 years ago, the generalized arteritis is now recognized as an important and significant cause of morbidity in elderly people; its cause and pathogenesis is poorly understood. Glucocorticosteroids are the drug of choice in all clinical types of GCA.
E, Nordborg +4 more
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Whereas giant cell arteritis (GCA) was considered a rare disease 50 years ago, the generalized arteritis is now recognized as an important and significant cause of morbidity in elderly people; its cause and pathogenesis is poorly understood. Glucocorticosteroids are the drug of choice in all clinical types of GCA.
E, Nordborg +4 more
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Current Treatment Options in Neurology, 1999
Diagnosis and management of giant cell (temporal) arteritis (GCA) should be performed by physicians who can accurately monitor the ophthalmologic, neurologic, and systemic sequelae of the disease as well as the numerous side effects of systemic corticosteroids, which are typically necessary for treatment.
, Turbin, , Kupersmith
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Diagnosis and management of giant cell (temporal) arteritis (GCA) should be performed by physicians who can accurately monitor the ophthalmologic, neurologic, and systemic sequelae of the disease as well as the numerous side effects of systemic corticosteroids, which are typically necessary for treatment.
, Turbin, , Kupersmith
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Neurologic Clinics, 2019
"Giant cell arteritis (GCA) is a chronic, idiopathic, granulomatous vasculitis of medium and large arteries comprising overlapping phenotypes of cranial arteritis and extracranial GCA. Vascular complications are generally due to delay in diagnosis and initiation of effective treatment.
Karina, Lazarewicz, Pippa, Watson
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"Giant cell arteritis (GCA) is a chronic, idiopathic, granulomatous vasculitis of medium and large arteries comprising overlapping phenotypes of cranial arteritis and extracranial GCA. Vascular complications are generally due to delay in diagnosis and initiation of effective treatment.
Karina, Lazarewicz, Pippa, Watson
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Neurologic Clinics, 2010
Giant cell arteritis is a systemic vasculitis with a wide clinical spectrum, and it represents a medical emergency. Visual loss is the most feared complication, and when it happens, it tends to be profound and permanent. Prompt diagnosis and treatment are imperative to minimize potentially devastating visual loss and neurologic deficits.
openaire +2 more sources
Giant cell arteritis is a systemic vasculitis with a wide clinical spectrum, and it represents a medical emergency. Visual loss is the most feared complication, and when it happens, it tends to be profound and permanent. Prompt diagnosis and treatment are imperative to minimize potentially devastating visual loss and neurologic deficits.
openaire +2 more sources