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Immunology of Giant Cell Arteritis
Circulation Research, 2023Giant cell arteritis is an autoimmune disease of medium and large arteries, characterized by granulomatous inflammation of the three-layered vessel wall that results in vaso-occlusion, wall dissection, and aneurysm formation.
C. Weyand, J. Goronzy
semanticscholar +1 more source
Seminars in Ophthalmology, 2008
This review summarizes the diagnosis, clinical manifestations and management of giant cell arteritis. Giant cell arteritis is an immune-mediated vasculitis of medium to large sized arteries that affects individuals older than the age of 50. Patients typically present with signs of vascular insufficiency of the extracranial arteries of the head and ...
Rochella A. Ostrowski +3 more
+11 more sources
This review summarizes the diagnosis, clinical manifestations and management of giant cell arteritis. Giant cell arteritis is an immune-mediated vasculitis of medium to large sized arteries that affects individuals older than the age of 50. Patients typically present with signs of vascular insufficiency of the extracranial arteries of the head and ...
Rochella A. Ostrowski +3 more
+11 more sources
Best Practice & Research Clinical Rheumatology, 2016
Giant cell arteritis (GCA) is the most common vasculitis of the elderly. The diagnosis can be challenging at times because of the limitation of the American Rheumatology Association (ARA) classification criteria and the significant proportion of biopsy-negative patients with GCA.
Christopher Hill +3 more
+10 more sources
Giant cell arteritis (GCA) is the most common vasculitis of the elderly. The diagnosis can be challenging at times because of the limitation of the American Rheumatology Association (ARA) classification criteria and the significant proportion of biopsy-negative patients with GCA.
Christopher Hill +3 more
+10 more sources
Clinical & Experimental Ophthalmology, 2006
Giant cell, or temporal, arteritis is a vasculitis of the medium and large arteries that preferentially involves vessels originating from the arch of the aorta. Classically, this disease manifests in an older individual with new-onset persistent headache, an abnormal temporal artery on examination, and increased serum inflammatory markers. The level of
Todd J. Schwedt +2 more
+9 more sources
Giant cell, or temporal, arteritis is a vasculitis of the medium and large arteries that preferentially involves vessels originating from the arch of the aorta. Classically, this disease manifests in an older individual with new-onset persistent headache, an abnormal temporal artery on examination, and increased serum inflammatory markers. The level of
Todd J. Schwedt +2 more
+9 more sources
Neurologic Clinics, 2010
Giant cell arteritis is a medium- and large-vessel vasculitis, the most prevalent systemic vasculitis in subjects over age 60. Clinical features are miscellaneous and sometimes misleading. Elevated acute-phase responses, such as a high erythrocyte sedimentation rate and increased levels of C-reactive protein, are important clues to the diagnosis, which
Eric Liozon, Kim Heang Ly
openaire +6 more sources
Giant cell arteritis is a medium- and large-vessel vasculitis, the most prevalent systemic vasculitis in subjects over age 60. Clinical features are miscellaneous and sometimes misleading. Elevated acute-phase responses, such as a high erythrocyte sedimentation rate and increased levels of C-reactive protein, are important clues to the diagnosis, which
Eric Liozon, Kim Heang Ly
openaire +6 more sources
American Journal of Roentgenology, 2003
Giant cell arteritis is the most common vasculitis in Caucasians. The aetiology of this disease remains uncertain. This article reviews some of the recent work in epidemiology and pathology in this field, with particular regard to the immunohistochemical findings in temporal artery biopsy specimens.
Thomas M. Seay +5 more
openaire +6 more sources
Giant cell arteritis is the most common vasculitis in Caucasians. The aetiology of this disease remains uncertain. This article reviews some of the recent work in epidemiology and pathology in this field, with particular regard to the immunohistochemical findings in temporal artery biopsy specimens.
Thomas M. Seay +5 more
openaire +6 more sources