Results 31 to 40 of about 5,817,209 (301)
Journal of Orthopaedic Reports, 2023 Background and purpose: Localized tenosynovial giant cell tumors represent a rare benign proliferative disorder of the synovial and surrounding tissue. This condition has insidious and unspecific symptoms that make its diagnosis challenging.
Luís Alves +4 more
doaj +1 more source
Giant cell tumor of the sacrum
Baylor University Medical Center Proceedings, 2020 Giant cell tumor of the sacrum is a rare primary tumor in a challenging anatomical location without clear consensus on treatment. We present a case of giant cell tumor of the sacrum and subsequent treatment with preoperative embolization, L5 to S4 laminectomy, partial sacrectomy, intraoperative thermal ablation, and L4 to pelvis stabilization and ...
James Rizkalla +4 more
openaire +3 more sources
Giant Cell Tumor of the Larynx
Ear, Nose & Throat Journal, 1993 A case of giant cell tumor of the larynx is reported. Only two previous cases were reported in the English literature. A review of giant cell tumors is reported. The specific pathologic findings and treatment recommendations for this condition are discussed.
G L, Murrell, H J, Lantz
openaire +2 more sources
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Giant Cell Tumor of the Tendon Sheath Causing Tarsal Tunnel Syndrome : A Case Report
, 2012 Tarsal tunnel syndrome is defined as a compressive neuropathy of posterior tibial nerve and its branches, medial and lateral plantar nerves , within the tarsal tunnel, which is located in the limited space behind medial malleolus. Giant cell tumor of the
WANG, CHENG-WEI;CHEN, CHIH-YU;WU, KARL;YANG, RONG-SEN +1 more
core +1 more source
Immunohistochemical analyses of beta-catenin and cyclin D1 expression in giant cell tumor of bone (GCTB): A possible role of Wnt pathway in GCTB tumorigenesis. [PDF]
, 2009 Giant cell tumor of bone (GCTB) is a benign neoplasm but occasionally shows local recurrence, and histologically consists of osteoclast-like giant cells (GC) and stromal mononuclear cells (SC), which are capable of proliferation and osteoblastic ...
Nakashima, Masahiro +7 more
core +1 more source
An intraosseous giant cell granuloma: An uncommon presentation
Journal of Pharmacy and Bioallied Sciences, 2021 The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant.
V Ravi Pavan +3 more
doaj +1 more source
Exploring functional mechanisms underlying tumor initiation, EMT and cell migration [PDF]
, 2012 Cancer is one of the leading causes of death. A primary tumor forms when cells start to proliferate in an uncontrolled way and stop reacting to restraining signals.
Gruber, Dorothea Cornelia
core +1 more source
Multicentric Giant Cell Tumor of Bone
, 2023 The typical presentation of giant cell tumor of bone is a solitary lesion involving the meta-epiphyseal region of the long bones. The presence of more than one distinct giant cell tumor in the same patient is rare.
Davide Maria Donati +13 more
core +2 more sources
Giant cell tumor of bone: risk factors for recurrence [PDF]
, 2011 Many surgeons treat giant cell tumor of bone (GCT) with intralesional curettage. Wide resection is reserved for extensive bone destruction where joint preservation is impossible or when expendable sites (eg, fibular head) are affected.
Franklin H. Sim +9 more
core +2 more sources